5-Phenyl-5-(trifluoromethyl)imidazolidine-2,4-dione

Base Information

Chemical Name:5-Phenyl-5-(trifluoromethyl)imidazolidine-2,4-dione
CAS No.:783-61-9
Molecular Formula:C10H7F3N2O2
Molecular Weight:244.173
Hs Code.:
DSSTox Substance ID:DTXSID10999653
Nikkaji Number:J2.535.657H

Synonyms:5-phenyl-5-(trifluoromethyl)imidazolidine-2,4-dione;158221-26-2;783-61-9;BRN 0802979;5-Phenyl-5-(trifluoromethyl)hydantoin;Hydantoin, 5-phenyl-5-(trifluoromethyl)-;SCHEMBL14101183;DTXSID10999653;QQEXOAWOBWITDK-UHFFFAOYSA-N;AKOS033199665;CS-0349269;EN300-64469;4-Phenyl-4-(trifluoromethyl)-4H-imidazole-2,5-diol;5-phenyl-5-(trifluoromethyl)-2,4-imidazolidinedione;(+/-)-5-phenyl-5-trifluoromethyl-imidazolidine-2,4-dione

Suppliers and Price of 5-Phenyl-5-(trifluoromethyl)imidazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 5-Phenyl-5-(trifluoromethyl)imidazolidine-2,4-dione

Chemical Property:

Density:1.44g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:244.04596196
Heavy Atom Count:17
Complexity:350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C(F)(F)F

Technology Process of 5-Phenyl-5-(trifluoromethyl)imidazolidine-2,4-dione

There total 6 articles about 5-Phenyl-5-(trifluoromethyl)imidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: potassium cyanide

: 434-45-7
2,2,2-Trifluoroacetophenone

: ammonium bicarbonate

: 783-61-9
5-Phenyl-5-(trifluormethyl)imidazolidin-2,4-dion

Guidance literature:: With ammonium hydroxide; In ethanol; water; at 65 ℃; for 72h;
DOI:10.1016/j.tetasy.2010.11.029

Reference yield: 53.0%

: potassium cyanide

: 434-45-7
2,2,2-Trifluoroacetophenone

: 506-87-6,6721-33-1,10361-29-2
ammonium carbonate

: 783-61-9
5-Phenyl-5-(trifluormethyl)imidazolidin-2,4-dion

Guidance literature:: In ethanol; water; at 110 - 120 ℃; for 38h; Autoclave;
DOI:10.1016/j.tetasy.2010.11.029

Reference yield:

: 2-Benzyloxycarbonylamino-3,3,3-trifluoro-2-phenyl-propionic acid methyl ester

: 783-61-9
5-Phenyl-5-(trifluormethyl)imidazolidin-2,4-dion

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / H₂ / Pd/C / methanol

2: toluene / 0.5 h

3: H₂O / acetone

With water; hydrogen; palladium on activated charcoal; In methanol; acetone; toluene;