Bicyclo[2.2.1]heptan-7-ol

Base Information

• Chemical Name: Bicyclo[2.2.1]heptan-7-ol
• CAS No.: 2566-48-5
• Molecular Formula: C7H12 O
• Molecular Weight: 112.172
• DSSTox Substance ID: DTXSID10180362
• Nikkaji Number: J110.429B
• Wikidata: Q83050892
• Mol file: 2566-48-5.mol

Synonyms:Bicyclo[2.2.1]heptan-7-ol;7-Norbornanol;2566-48-5;Bicyclo(2.2.1)heptan-7-ol;7-Norborneol;7-Hydroxynorbornane;7-Bicyclo(2.2.1)heptanol;SCHEMBL1721586;SCHEMBL18923907;DTXSID10180362;QSOLQDIOEJREPU-UHFFFAOYSA-N;CS-0057898

Chemical Property of Bicyclo[2.2.1]heptan-7-ol

Chemical Property:

• Vapor Pressure: 0.15mmHg at 25°C
• Melting Point: 117-118 °C
• Boiling Point: 190°C at 760 mmHg
• PKA: 15.04±0.20(Predicted)
• Flash Point: 74.4°C
• PSA: 20.23000
• Density: 1.097g/cm³
• LogP: 1.16730
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 112.088815002
• Heavy Atom Count: 8
• Complexity: 80.6

Purity/Quality:

95-99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2CCC1C2O

Technology Process of Bicyclo[2.2.1]heptan-7-ol

There total 2 articles about Bicyclo[2.2.1]heptan-7-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

norbornene (279-23-2) → Norbornan-2-on (497-38-1) + 7-norbornanol (2566-48-5) + exo-2-norbornanol (497-37-0) + (+/-)-endo-2-norborneol (497-36-9) + exo-2-norbornyl chloride (67844-27-3) + endo-2-norbornyl chloride (765-91-3,2999-06-6,29342-53-8,36025-11-3,67844-26-2,67844-27-3,130726-60-2)

Guidance literature:

With tetrachloromethane; ozone; at 25 ℃; Rate constant; Product distribution; Mechanism; other norbornane derivatives, var. temperatures; E_a, log A per H;

DOI:10.1021/jo00250a005

Reference yield:

(-)-nortricyclanol (695-04-5,70981-39-4,70981-40-7) → 7-norbornanol (2566-48-5) + exo-norborneol (61277-90-5) + (2R)-(+)-exo-2-norborneol (497-37-0)

Guidance literature:

With hydrogen; platinum(IV) oxide; In acetic acid; Yield given. Yields of byproduct given; Ambient temperature;

Reference yield: 68.0%

7-norbornanol (2566-48-5) + 1-ethynylcyclohexyl 2,3,4,6-tetra-O-benzyl α-D-mannopyranoside (1384752-77-5) → bicyclo[2.2.1]heptan-7yl 2,3,4,6-tetra-O-benzyl α-D-mannopyranoside (1384752-84-4)

Guidance literature:

With gold(III) chloride; silver hexafluoroantimonate; In dichloromethane; acetonitrile; at 20 ℃; for 8h; Inert atmosphere;

DOI:10.1039/c2cc32649c

upstream raw materials:

norbornene

(-)-nortricyclanol

Downstream raw materials:

acetone

7-norbornanone

7-Norbornyl-methylaether

Aethyl-α-methylen-7-norbornanacetat