11-Dehydro-thromboxane B2

Base Information

Chemical Name:11-Dehydro-thromboxane B2
CAS No.:67910-12-7
Molecular Formula:C₂₀H₃₂O₆
Molecular Weight:368.47
Hs Code.:
UNII:CJ6ST9UG7C
ChEMBL ID:CHEMBL1405272
Metabolomics Workbench ID:2593
Nikkaji Number:J265.059B
Wikidata:Q2806929
Wikipedia:11-Dehydrothromboxane_B2
Mol file:67910-12-7.mol

Synonyms:11-dehydro-thromboxane B2;11-dehydro-TXB2;11-dehydrothromboxane B2;11-keto-thromboxane B2

Suppliers and Price of 11-Dehydro-thromboxane B2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
11-DehydroThromboxaneB2(85%)
1mg
$ 2285.00

Cayman Chemical
11-dehydro Thromboxane B2 ≥98%
250μg
$ 382.00

Cayman Chemical
11-dehydro Thromboxane B2 ≥98%
100μg
$ 171.00

Cayman Chemical
11-dehydro Thromboxane B2 ≥98%
50μg
$ 91.00

Cayman Chemical
11-dehydro Thromboxane B2 ≥98%
1mg
$ 1076.00

Biosynth Carbosynth
11-Dehydro thromboxane B2
5 mg
$ 5850.00

Biosynth Carbosynth
11-Dehydro thromboxane B2
2 mg
$ 4000.00

Biosynth Carbosynth
11-Dehydro thromboxane B2
500 ug
$ 1680.00

American Custom Chemicals Corporation
11-DEHYDRO THROMBOXANE B2 95.00%
5MG
$ 495.33

AK Scientific
11-DehydrothromboxaneB2
1mg
$ 1444.00

Total 12 raw suppliers

Chemical Property of 11-Dehydro-thromboxane B2

Chemical Property:

Appearance/Colour:colorless oil
Vapor Pressure:2.67E-16mmHg at 25°C
Boiling Point:588.5 °C at 760 mmHg
PKA:4.76±0.10(Predicted)
Flash Point:202.9 °C
PSA：104.06000
Density:1.167 g/cm³
LogP:2.97760
Storage Temp.:Amber Vial, -20°C Freezer, Under Inert Atmosphere
Solubility.:Acetonitrile (Slightly), Chloroform (Slightly)
XLogP3:2.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:368.21988874
Heavy Atom Count:26
Complexity:485

Purity/Quality:

99% ^*data from raw suppliers

11-DehydroThromboxaneB2(85%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(C=CC1C(C(CC(=O)O1)O)CC=CCCCC(=O)O)O
Isomeric SMILES:CCCCC[C@@H](/C=C/[C@@H]1[C@H]([C@H](CC(=O)O1)O)C/C=C\CCCC(=O)O)O
Uses A metabolite of Thromboxane that is an in vivo markers of oxidative stress and platelet activation. It is associated with adverse cardiovascular events in Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT). A metabolite of Thromboxane that is an in vivo markers of oxidative stress and platelet activation. It is associated with adverse cardiovascular events in Alzheimer''s Disease Anti-inflammatory Prevention Trial (ADAPT).

Technology Process of 11-Dehydro-thromboxane B2

There total 1 articles about 11-Dehydro-thromboxane B2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41598-07-6
prostaglandin D₂

: 5-trans-prostaglandin D₂

: C₂₀H₃₂O₆

: 67910-12-7
11-Dehydrothromboxane B₂

Guidance literature:: With hydrogenchloride; dihydrogen peroxide; In water; at 20 ℃; for 1h;
DOI:10.1002/lipd.12206

Reference yield:

: 67910-12-7
11-Dehydrothromboxane B₂

: 146038-31-5
(Z)-(8S,9S)-8-[(E)-(1R,4S)-1,4-Bis-(ethyl-dimethyl-silanyloxy)-non-2-enyl]-9-(ethyl-dimethyl-silanyloxy)-undec-5-enedioic acid 1-methyl ester 11-pentafluorophenylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: diethyl ether

2: 1) NH₄HCO₃, pyridine, 2) i-Pr₂NEt / 1) 3 h, r.t., 2) MeCN, 40 deg C, 30 min

3: pyridine / 0.25 h / 40 °C

With pyridine; ammonium bicarbonate; N-ethyl-N,N-diisopropylamine; In diethyl ether;
DOI:10.1002/oms.1210271130

Reference yield:

: 67910-12-7
11-Dehydrothromboxane B₂

: (Z)-(8S,9S)-8-((E)-(1R,4S)-1,4-Dihydroxy-non-2-enyl)-9-hydroxy-undec-5-enedioic acid 1-methyl ester 11-pentafluorophenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether

2: 1) NH₄HCO₃, pyridine, 2) i-Pr₂NEt / 1) 3 h, r.t., 2) MeCN, 40 deg C, 30 min

With pyridine; ammonium bicarbonate; N-ethyl-N,N-diisopropylamine; In diethyl ether;
DOI:10.1002/oms.1210271130