2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one

Base Information

• Chemical Name: 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one
• CAS No.: 7145-87-1
• Molecular Formula: C16H14 Br2 O2
• Molecular Weight: 398.094
• Mol file: 7145-87-1.mol

Synonyms:Propiophenone,2,3-dibromo-4'-methoxy-3-phenyl- (7CI,8CI); 4-Methoxychalcone dibromide; NSC74708

Chemical Property of 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one

Chemical Property:

• Vapor Pressure: 8.92E-09mmHg at 25°C
• Boiling Point: 463.7°Cat760mmHg
• Flash Point: 234.2°C
• Density: 1.594g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one

There total 11 articles about 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4'-methoxychalcone (959-23-9) → 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one (7145-87-1)

Guidance literature:

With ammonium peroxydisulfate; ammonium bromide; In water; at 20 ℃; for 0.583333h; chemoselective reaction; Milling; Green chemistry;

Reference yield: 57.0%

4'-methoxychalcone (959-23-9) → 2-bromo-3-hydroxy-1-(4-methoxyphenyl)-3-phenylpropan-1-one + 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one (7145-87-1,24213-12-5)

Guidance literature:

With iodine pentoxide; water; potassium bromide; In acetonitrile; at 20 ℃; for 23h; diastereoselective reaction; Green chemistry;

DOI:10.1016/j.tetlet.2014.03.064

Reference yield:

4'-methoxychalcone (959-23-9) → 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one (7145-87-1,24213-12-5) + 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one

Guidance literature:

With N-Bromosuccinimide; dimanganese decacarbonyl; In 1,2-dichloro-ethane; at 110 ℃; for 12h; Overall yield = 85 percent; Schlenk technique;

DOI:10.1039/d1cc04534b

upstream raw materials:

4'-methoxychalcone

cinnamoyl chloride

methoxybenzene

trans-4'-methoxychalcone

Downstream raw materials:

1-(4-methoxy-phenyl)-3-phenyl-2,3-dipiperidino-propan-1-one

(Z)-2-bromo-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one

1,3,6,8-tetramethyl-1H,3H,6H,8H-pyrimido[4,5-g]pteridine-2,4,7,9-tetraone

2-diethylamino-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one