Technology Process of 2,3,5-Trihydroxytoluene
There total 15 articles about 2,3,5-Trihydroxytoluene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethyl acetate;
at 45 ℃;
for 3h;
under 3000.24 Torr;
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
at 25 ℃;
for 12h;
DOI:10.1021/ja00156a005
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 98 percent / H2, AcOH / 10percent Pd/C / ethyl acetate / 72 h
2: 70 percent / aq. KH2PO4, (KSO3)2NO / diethyl ether / 1 h
3: 98 percent / aq. TiCl3 / acetone / 0.17 h / Ambient temperature
4: 28 percent / K2CO3 / acetone / 12 h / Heating
5: 66 percent / BBr3 / CH2Cl2 / 12 h / 25 °C
With
potassium dihydrogenphosphate; titanium(III) chloride; potassium nitrososulfonate; hydrogen; boron tribromide; potassium carbonate; acetic acid;
palladium on activated charcoal;
In
diethyl ether; dichloromethane; ethyl acetate; acetone;
DOI:10.1021/ja00156a005
