4-Bromothiophene-3-carboxamide

Base Information

Chemical Name:4-Bromothiophene-3-carboxamide
CAS No.:100245-61-2
Molecular Formula:C5H4BrNOS
Molecular Weight:206.063
Hs Code.:
European Community (EC) Number:664-259-7
DSSTox Substance ID:DTXSID10596666
Wikidata:Q82491974
Mol file:100245-61-2.mol

Synonyms:4-Bromothiophene-3-carboxamide;100245-61-2;3-Thiophenecarboxamide, 4-bromo-;4-Bromothiophene-3-carboxylic acid amide;4-bromo-3-thiophene-formamide;SCHEMBL3854074;DTXSID10596666;BMZBDWPOBVGKSU-UHFFFAOYSA-N;MFCD17171292;4-Bromothiophene-3-carboxamide, 97%;AKOS027253223;AS-43035;DB-099849;CS-0086828;EN300-2177066

Suppliers and Price of 4-Bromothiophene-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of 4-Bromothiophene-3-carboxamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:204.91970
Heavy Atom Count:9
Complexity:130

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(C(=CS1)Br)C(=O)N

Technology Process of 4-Bromothiophene-3-carboxamide

There total 3 articles about 4-Bromothiophene-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 16694-17-0
4-bromo-3-thiophenecarboxylic acid

: 100245-61-2
4-bromothiophene-3-carboxamide

Guidance literature:: 4-bromo-3-thiophenecarboxylic acid; With thionyl chloride; N,N-dimethyl-formamide; In tetrahydrofuran; at 10 - 25 ℃;

With hydrogenchloride; ammonia; In tetrahydrofuran; water; N,N-dimethyl-formamide; at -10 - 30 ℃; for 1h;
DOI:10.1021/jo9003772

Reference yield:

: 18895-10-8
4-bromothiophene-3-carbonitrile

: 100245-61-2
4-bromothiophene-3-carboxamide

Guidance literature:: With dihydrogen peroxide; potassium carbonate;

Reference yield:

: 18791-95-2
4-bromothiophene-3-carbaldehyde oxime

: 100245-61-2
4-bromothiophene-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: Ac₂O

2: H₂O₂, aq. K₂CO₃

With dihydrogen peroxide; acetic anhydride; potassium carbonate;