4-(4-Methoxyphenyl)isoquinoline

Base Information

Chemical Name:4-(4-Methoxyphenyl)isoquinoline
CAS No.:101273-53-4
Molecular Formula:C16H13NO
Molecular Weight:235.285
Hs Code.:
DSSTox Substance ID:DTXSID60400527
Nikkaji Number:J3.385.727F
Mol file:101273-53-4.mol

Synonyms:4-(4-methoxyphenyl)isoquinoline;101273-53-4;Isoquinoline, 4-(4-methoxyphenyl)-;SCHEMBL4214556;DTXSID60400527

Suppliers and Price of 4-(4-Methoxyphenyl)isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(4-Methoxyphenyl)isoquinoline

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:235.099714038
Heavy Atom Count:18
Complexity:260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CN=CC3=CC=CC=C32

Technology Process of 4-(4-Methoxyphenyl)isoquinoline

There total 11 articles about 4-(4-Methoxyphenyl)isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1532-97-4
4-bromoisoquinoline

: 5720-07-0
4-methoxyphenylboronic acid

: 101273-53-4
4-(4-methoxyphenyl) isoquinoline

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; N,N-dimethyl-formamide; at 80 ℃;
DOI:10.1007/s00044-020-02642-0

Reference yield: 72.0%

: 104-92-7
1-bromo-4-methoxy-benzene

: 93830-62-7
diethyl (4-isoquinolyl)borane

: 101273-53-4
4-(4-methoxyphenyl) isoquinoline

Guidance literature:: With potassium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutylammomium bromide; In tetrahydrofuran; for 6h; Heating;

Reference yield: 68.0%

: 50624-28-7
1-(isoquinolin-2(1H)-yl)ethan-1-one

: 5720-07-0
4-methoxyphenylboronic acid

: 101273-53-4
4-(4-methoxyphenyl) isoquinoline

Guidance literature:: With palladium(II) trifluoroacetate; copper(II) bis(trifluoromethanesulfonate); trifluoroacetic acid; silver(l) oxide; at 70 ℃; for 8h; regioselective reaction; Inert atmosphere;
DOI:10.1039/c4cc03165b