1-Bromo-2-[(2-methylprop-2-en-1-yl)oxy]benzene

Base Information

• Chemical Name: 1-Bromo-2-[(2-methylprop-2-en-1-yl)oxy]benzene
• CAS No.: 10178-53-7
• Molecular Formula: C10H11BrO
• Molecular Weight: 227.101
• DSSTox Substance ID: DTXSID20538138
• Nikkaji Number: J879.762E
• Wikidata: Q82413371
• Mol file: 10178-53-7.mol

Synonyms:10178-53-7;1-Bromo-2-[(2-methylprop-2-en-1-yl)oxy]benzene;Benzene, 1-bromo-2-[(2-methyl-2-propen-1-yl)oxy]-;1-bromo-2-(2-methylprop-2-enoxy)benzene;SCHEMBL2112699;HPZXEWQLFFUHHD-UHFFFAOYSA-;DTXSID20538138;AKOS000191422;1-Bromo-2-((2-methylallyl)oxy)benzene;CS-0256583;EN300-6498556;InChI=1/C10H11BrO/c1-8(2)7-12-10-6-4-3-5-9(10)11/h3-6H,1,7H2,2H3

Chemical Property of 1-Bromo-2-[(2-methylprop-2-en-1-yl)oxy]benzene

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 225.99933
• Heavy Atom Count: 12
• Complexity: 156

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)COC1=CC=CC=C1Br

Technology Process of 1-Bromo-2-[(2-methylprop-2-en-1-yl)oxy]benzene

There total 6 articles about 1-Bromo-2-[(2-methylprop-2-en-1-yl)oxy]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

2-methyl-3-bromo-1-propene (1458-98-6) + 2-hydroxybromobenzene (95-56-7) → 1-bromo-2-((2-methylallyl)oxy)benzene (10178-53-7)

Guidance literature:

With potassium carbonate; In acetone; under 760.051 Torr; Inert atmosphere; Reflux;

Reference yield: 95.0%

2-hydroxybromobenzene (95-56-7) + 3-Chloro-2-methylpropene (563-47-3) → 1-bromo-2-((2-methylallyl)oxy)benzene (10178-53-7)

Guidance literature:

With potassium carbonate; sodium iodide; In acetone; for 20h; Heating;

DOI:10.1007/BF00808952

Reference yield: 92.0%

3-chloro-2-[(methyloxy)methyl]-1-propene (886883-34-7) + 2-hydroxybromobenzene (95-56-7) → 1-bromo-2-((2-methylallyl)oxy)benzene (10178-53-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃;

DOI:10.1021/acs.joc.5b01024

upstream raw materials:

2-hydroxybromobenzene

3-Chloro-2-methylpropene

2-methyl-3-bromo-1-propene

2-methylallyl methanesulfonate

Downstream raw materials:

diethyl o-(2-methylallyloxy)phenylmalonate

3,3-dimethyl-2,3-dihydrobenzo[b]furan

3-methylisochroman

methylallyl phenyl ether