Chemical Property of 3-Chloro-2-methylpropene
Chemical Property:
- Appearance/Colour:clear liquid
- Vapor Pressure:102 mm Hg ( 20 °C)
- Melting Point:-80 °C
- Refractive Index:n20/D 1.427(lit.)
- Boiling Point:72.5 °C at 760 mmHg
- Flash Point:9 °F
- PSA：0.00000
- Density:0.897 g/cm3
- LogP:1.80130
- Storage Temp.:Refrigerator (+4°C) + Flammables area
- Solubility.:H2O: insoluble
- Water Solubility.:0.5 g/L (20 ºC)
- XLogP3:2.1
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:0
- Rotatable Bond Count:1
- Exact Mass:90.0236279
- Heavy Atom Count:5
- Complexity:38.9
- Transport DOT Label:Flammable Liquid
- Purity/Quality:
-
98% *data from raw suppliers
3-Chloro-2-methyl-1-propene *data from reagent suppliers
Safty Information:
- Pictogram(s):
F, 
C, 
N
- Hazard Codes:F,C,N
- Statements:
11-20/22-34-43-51/53
- Safety Statements:
9-16-29-36/37/39-45-61-26
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Chemical Classes:Other Classes -> Halogenated Aliphatics, Unsaturated
- Canonical SMILES:CC(=C)CCl
- Inhalation Risk:A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
- Effects of Short Term Exposure:Lachrymation. The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. Exposure at high levels could cause lowering of consciousness.
- Effects of Long Term Exposure:Repeated or prolonged contact may cause skin sensitization.
-
Description
3-Chloro-2-methylpropene is used as an intermediate to produce carbofuran, herbicides, plastics, pharmaceuticals and other organics. It is also used as an additive in textile and perfumes. It was used to study ring opening polymerization of oxirane derivatives using organotin phosphate condensate and cationic polymerization of 3-Chloro-2-methylpropene with AICI3 and AIBr3 as initiators. It is also the reactant for the synthesis of cyclobutanone.
-
Uses
3-Chloro-2-methylpropene has been used as reactant in the synthesis of cyclobutanone. It is used as an intermediate in the production of plastics, pharmaceuticals and other organic chemicals. 3-Chloro-2-methyl-1-propene was used to study ring opening polymerization of oxirane derivatives using organotin phosphate condensate. It was used to study cationic polymerization of 3-Chloro-2-methyl-1-propene using using AICI3 and A3IBr, as initiators.
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Biological Functions
MAC is a valuable index for clinical anesthesia, but it is
seldom employed without taking other factors into consideration.
For example, inhibiting movement in only
50% of patients is not acceptable. Consequently, if an
inhalational agent were being used alone—that is, without
the administration of other anesthetics or analgesic
drugs—the anesthesiologist would employ a multiple of
its MAC value to ensure immobility.MAC is frequently
multiplied by a factor of 1.3 to achieve nearly 100%
clinical efficacy. On the other hand, useful clinical results
may be achieved with doses of anesthetics below
MAC levels. For example, mild analgesia and amnesia
often occur with doses of inhalational agents that are
near 0.5 MAC. In this state, it may even be possible to
communicate with patients intraoperatively, while their
recall is limited.
