Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl )diphenylmethyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite]

Base Information

Chemical Name:Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl )diphenylmethyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite]
CAS No.:101904-22-7
Molecular Formula:C49H63N4O8PSi
Molecular Weight:895.12
Hs Code.:
Mol file:101904-22-7.mol

Cytidine,
N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl
)diphenylmethyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite]

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl )diphenylmethyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite]

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MSDS Files:: SDS file from LookChem

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Technology Process of Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl )diphenylmethyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite]

There total 1 articles about Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl )diphenylmethyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 86030-43-5
N,N-diisopropylmethylphosphonamidic chloride

: 72409-30-4
N⁴-benzoyl-2'-O-(tert-butyldimethylsilyl)-5'-O-(4-monomethoxytrityl)cytidine

: 101904-22-7
N⁴-benzoyl-5'-O-(monomethoxytrityl)-2'-O-(tert-butyldimethylsilyl)cytidine 3'-N,N-diisopropylmethylphosphoramidite

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; for 3h; Ambient temperature;
DOI:10.1021/ja00259a037

Reference yield:

: 101904-22-7
N⁴-benzoyl-5'-O-(monomethoxytrityl)-2'-O-(tert-butyldimethylsilyl)cytidine 3'-N,N-diisopropylmethylphosphoramidite

: 29108-90-5
2',3'-di-O-acetyl-uridine

: 128216-96-6
C₅₆H₆₄N₅O₁₇PSi

Guidance literature:: With 1H-tetrazole; 2,3,5-trimethyl-pyridine; iodine; Yield given. Multistep reaction; 1) THF, RT, 3 h, 2) water, THF, 10 min;
DOI:10.1021/jo00302a044