alpha-(Chloromethyl)-2-nitroimidazole-1-ethanol

Base Information Edit

Chemical Name:alpha-(Chloromethyl)-2-nitroimidazole-1-ethanol
CAS No.:13551-86-5
Molecular Formula:C6H8ClN3O3
Molecular Weight:205.601
Hs Code.:2933290090
DSSTox Substance ID:DTXSID70875661
Nikkaji Number:J964D
Mol file:13551-86-5.mol

Synonyms:13551-86-5;1-chloro-3-(2-nitroimidazol-1-yl)propan-2-ol;alpha-(Chloromethyl)-2-nitroimidazole-1-ethanol;BRN 0613157;Ro-07-0269;1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole;alpha-Chloromethyl-2-nitro-1H-imidazole-1-ethanol;Imidazole-1-ethanol, alpha-(chloromethyl)-2-nitro-;1H-Imidazole-1-ethanol, alpha-(chloromethyl)-2-nitro-;C6H8ClN3O3;1-(2-nitro-1-imidazolyl)-3-chloro-2-propanol;1-Chloro-3-(2-nitro-imidazol-1-yl)-propan-2-ol;SCHEMBL1615079;C6-H8-Cl-N3-O3;DTXSID70875661;Ro 7-0269;LS-78600;1(3-CL-2-OH PR)-2-NO2-IMIDAZOLE;1-(2-Hydroxy-3-chloropropyl)-2-nitroimidazole;alpha-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol;Imidazole-1-ethanol, .alpha.-(chloromethyl)-2-nitro-;1H-Imidazole-1-ethanol, .alpha.-(chloromethyl)-2-nitro-;1H-Imidazole-1-ethanol, alpha-(chloromethyl)-2-nitro- (9CI)

Suppliers and Price of alpha-(Chloromethyl)-2-nitroimidazole-1-ethanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
α-(chloromethyl)-2-nitro-1H-Imidazole-1-ethanol 97.00%
25G
$ 3680.00

AccelPharmtech
α-(chloromethyl)-2-nitro-1H-Imidazole-1-ethanol 97.00%
5G
$ 1970.00

AccelPharmtech
α-(chloromethyl)-2-nitro-1H-Imidazole-1-ethanol 97.00%
1G
$ 1160.00

Total 2 raw suppliers

Chemical Property of alpha-(Chloromethyl)-2-nitroimidazole-1-ethanol Edit

Chemical Property:

Vapor Pressure:1.64E-08mmHg at 25°C
Boiling Point:439.8°C at 760 mmHg
Flash Point:219.8°C
PSA：83.87000
Density:1.6g/cm³
LogP:0.91420
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:205.0254188
Heavy Atom Count:13
Complexity:187

Purity/Quality:

99% ^*data from raw suppliers

α-(chloromethyl)-2-nitro-1H-Imidazole-1-ethanol 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN(C(=N1)[N+](=O)[O-])CC(CCl)O
Uses 1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole is an intermediate in the synthesis of 1-(2,3-Epoxypropyl)-2-nitroimidazole (B592583) which is an intermediate in the synthesis of Pimonidazole-d10 (P447814). Isotope labelled Pimonidazole (P447813) is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It abels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.

Technology Process of alpha-(Chloromethyl)-2-nitroimidazole-1-ethanol

There total 3 articles about alpha-(Chloromethyl)-2-nitroimidazole-1-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%