Hexanoic acid, 2-ethyl-, 1,2,3,4,4a,5,6,7-octahydro-5-[(methoxymethoxy)methyl]-1-oxo-6-(phenyl methoxy)-2-(phenylmethyl)-7-isoquinolinyl ester

Base Information

Chemical Name:Hexanoic acid, 2-ethyl-, 1,2,3,4,4a,5,6,7-octahydro-5-[(methoxymethoxy)methyl]-1-oxo-6-(phenyl methoxy)-2-(phenylmethyl)-7-isoquinolinyl ester
CAS No.:102673-37-0
Molecular Formula:C34H45NO6
Molecular Weight:563.734
Hs Code.:
Mol file:102673-37-0.mol

Hexanoic acid, 2-ethyl-,
1,2,3,4,4a,5,6,7-octahydro-5-[(methoxymethoxy)methyl]-1-oxo-6-(phenyl
methoxy)-2-(phenylmethyl)-7-isoquinolinyl ester

Synonyms:

Suppliers and Price of Hexanoic acid, 2-ethyl-, 1,2,3,4,4a,5,6,7-octahydro-5-[(methoxymethoxy)methyl]-1-oxo-6-(phenyl methoxy)-2-(phenylmethyl)-7-isoquinolinyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Hexanoic acid, 2-ethyl-, 1,2,3,4,4a,5,6,7-octahydro-5-[(methoxymethoxy)methyl]-1-oxo-6-(phenyl methoxy)-2-(phenylmethyl)-7-isoquinolinyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Hexanoic acid, 2-ethyl-, 1,2,3,4,4a,5,6,7-octahydro-5-[(methoxymethoxy)methyl]-1-oxo-6-(phenyl methoxy)-2-(phenylmethyl)-7-isoquinolinyl ester

There total 4 articles about Hexanoic acid, 2-ethyl-, 1,2,3,4,4a,5,6,7-octahydro-5-[(methoxymethoxy)methyl]-1-oxo-6-(phenyl methoxy)-2-(phenylmethyl)-7-isoquinolinyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 100-39-0
benzyl bromide

: 96648-92-9
(4aR^*,5S^*,6S^*,7S^*)-2-benzyl-7-((2'-ethylhexanoyl)oxy)-3,4,4a,5,6,7-hexahydro-6-hydroxy-5-((methoxymethoxy)methyl)-1(2H)-isoquinolone

: 102673-37-0
(4aR^*,5S^*,6S^*,7S^*)-2-benzyl-6-(benzyloxy)-7-((2'-ethylhexanoyl)oxy)-3,4,4a,5,6,7-hexahydro-5-((methoxymethoxy)methyl)-1(2H)-isoquinolone

Guidance literature:: With calcium carbonate; silver(l) oxide; at 50 ℃; for 84h;
DOI:10.1016/S0040-4039(00)95001-9

Reference yield:

: 96648-91-8
(4aR^*,5S^*,6S^*,7R^*)-2-benzyl-3,4,4a,5,6,7-hexahydro-5-((methoxymethoxy)methyl)-6,7-oxy-1(2H)-isoquinolone

: 102673-37-0
(4aR^*,5S^*,6S^*,7S^*)-2-benzyl-6-(benzyloxy)-7-((2'-ethylhexanoyl)oxy)-3,4,4a,5,6,7-hexahydro-5-((methoxymethoxy)methyl)-1(2H)-isoquinolone

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / lithium 2-ethylhexanoate / 1,2-dimethoxy-ethane / 16 h / Heating

2: 76 percent / Ag₂O, CaSO₄ / 84 h / 50 °C

With calcium sulfate; lithium 2-ethylhexanoate; silver(l) oxide; In 1,2-dimethoxyethane;
DOI:10.1021/ja00254a036

Reference yield:

: 96648-90-7,109961-10-6
(4aR^*,5S^*)-2-benzyl-5-((methoxymethoxy)methyl)-3,4,4a,5-tetrahydro-1(2H)-isoquinolone

: 102673-37-0
(4aR^*,5S^*,6S^*,7S^*)-2-benzyl-6-(benzyloxy)-7-((2'-ethylhexanoyl)oxy)-3,4,4a,5,6,7-hexahydro-5-((methoxymethoxy)methyl)-1(2H)-isoquinolone

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 14 h / 0 °C

2: 90 percent / lithium 2-ethylhexanoate / 1,2-dimethoxy-ethane / 16 h / Heating

3: 76 percent / Ag₂O, CaSO₄ / 84 h / 50 °C

With calcium sulfate; lithium 2-ethylhexanoate; 3-chloro-benzenecarboperoxoic acid; silver(l) oxide; In 1,2-dimethoxyethane; dichloromethane;
DOI:10.1021/ja00254a036