4-Cyclopropylphenol

Base Information

• Chemical Name: 4-Cyclopropylphenol
• CAS No.: 10292-61-2
• Molecular Formula: C9H10O
• Molecular Weight: 134.178
• Hs Code.: 2907199090
• DSSTox Substance ID: DTXSID30450731
• Nikkaji Number: J570.188K
• Wikidata: Q72461054
• Mol file: 10292-61-2.mol

Synonyms:4-cyclopropylphenol;10292-61-2;4-Cyclopropyl phenol;Phenol, 4-cyclopropyl-;4-cyclopropyl-phenol;4-Cyclopropylphenol;p-Cyclopropylphenol;p-hydroxyphenylcyclopropane;SCHEMBL1865798;DTXSID30450731;IGIWPHRUBXKMAR-UHFFFAOYSA-N;AMY23808;MFCD06802405;RB3284;AKOS004118880;PS-5869;AC-30170;BB 0223487;CS-0028399;FT-0696396;EN300-1842412;A856573

Chemical Property of 4-Cyclopropylphenol

Chemical Property:

• Melting Point: 57-58℃
• Refractive Index: 1.5618 (589.3 nm 20℃)
• Boiling Point: 248.2±19.0℃ (760 Torr)
• PKA: 10.05±0.13(Predicted)
• Flash Point: 119.8±11.0℃
• PSA: 20.23000
• Density: 1.158±0.06 g/cm3 (20 oC 760 Torr)
• LogP: 2.26960
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 134.073164938
• Heavy Atom Count: 10
• Complexity: 110

Purity/Quality:

97% ^*data from raw suppliers

4-Cyclopropylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1C2=CC=C(C=C2)O

Technology Process of 4-Cyclopropylphenol

There total 14 articles about 4-Cyclopropylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4'-Cyclopropylphenyl acetate → 4-cyclopropylphenol (10292-61-2)

Guidance literature:

With methanol; sodium acetate; In tetrahydrofuran; for 2h;

Reference yield: 94.0%

diiodomethane (75-11-6) + p-acetoxystyrene (2628-16-2) → 4-cyclopropylphenol (10292-61-2)

Guidance literature:

diiodomethane; p-acetoxystyrene; With diethylzinc; In toluene; at 20 ℃; for 17h; Reflux;

With hydrogenchloride; In water; toluene;

With sodium carbonate; In tetrahydrofuran; methanol; at 20 ℃; for 2h;

Reference yield: 77.0%

2-(4-cyclopropylphenoxy)tetrahydro-2H-pyran → 4-cyclopropylphenol (10292-61-2)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; at 120 ℃; for 0.0833333h; Microwave irradiation;

upstream raw materials:

4-(prop-2-enyl)phenol

4-(4,5-dihydro-1H-pyrazol-3-yl)-phenol

4-cyclopropylaniline

cyclopropylbenzene

Downstream raw materials:

(4-cyclopropyl-phenoxy)-acetic acid methyl ester

(±)-3-(4-cyclopropylphenoxy)-1-(3-methoxy-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)pyrrolidin-2-one

3-(4-cyclopropylphenoxy)-1-(3-ethyl-4-(pyrrolidin-1-yl)phenyl)pyrrolidin-2-one

(±)-3-(4-cyclopropylphenoxy)-1-(3-methoxy-4-morpholinophenyl)pyrrolidin-2-one