4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]benzenesulfonamide

Base Information

Chemical Name:4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]benzenesulfonamide
CAS No.:10311-89-4
Molecular Formula:C16H14N2O4S
Molecular Weight:330.364
Hs Code.:
ChEMBL ID:CHEMBL4101260
DSSTox Substance ID:DTXSID101157617
Nikkaji Number:J3.184.735D
Mol file:10311-89-4.mol

Synonyms:CHEMBL4101260;SCHEMBL7825656;DTXSID101157617;BDBM50234458;NSC798878;NSC-798878;4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]benzenesulfonamide;10311-89-4

Suppliers and Price of 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]benzenesulfonamide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:330.06742811
Heavy Atom Count:23
Complexity:551

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)CCC3=CC=C(C=C3)S(=O)(=O)N

Technology Process of 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]benzenesulfonamide

There total 2 articles about 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 85-44-9
phthalic anhydride

: 35303-76-5
4-(2-aminoethyl)benzenesulfonamide

: 10311-89-4
4-(2-phthalimidoethyl) benzenesulfonamide

Guidance literature:: phthalic anhydride; 4-(2-aminoethyl)benzenesulfonamide; In N,N-dimethyl-formamide; at 70 ℃; for 4h;

With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 85-44-9
phthalic anhydride

: 6325-22-0,42286-14-6
chlorhydrate de (β-aminoethyl)-4 benzenesulfonamide

: 10311-89-4
4-(2-phthalimidoethyl) benzenesulfonamide

Guidance literature:: In N,N-dimethyl-formamide; Reflux; Alkaline conditions;
DOI:10.1016/j.bioorg.2019.103115

Reference yield: 81.0%

: 10311-89-4
4-(2-phthalimidoethyl) benzenesulfonamide

: 74-88-4
methyl iodide

: 1075732-29-4
C₁₈H₁₈N₂O₄S

Guidance literature:: 4-(2-phthalimidoethyl) benzenesulfonamide; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1.25h;

methyl iodide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.25h;