2-[(Naphthalen-1-yl)methylidene]butanedioic acid

Base Information

Chemical Name:2-[(Naphthalen-1-yl)methylidene]butanedioic acid
CAS No.:103632-74-2
Molecular Formula:C₁₅H₁₂O₄
Molecular Weight:256.258
Hs Code.:
DSSTox Substance ID:DTXSID20709306
Mol file:103632-74-2.mol

Synonyms:2-[(Naphthalen-1-yl)methylidene]butanedioic acid;SCHEMBL7328223;DTXSID20709306;OCEJTXWZGWBSPX-UHFFFAOYSA-N;2-(1-naphthylmethylene)succinic acid;2-(1-naphthylmethylene) succinic acid;(1-naphthalenylmethylene)butanedioic acid

Suppliers and Price of 2-[(Naphthalen-1-yl)methylidene]butanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-[(Naphthalen-1-yl)methylidene]butanedioic acid

Chemical Property:

PSA：74.60000
LogP:2.78250
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:256.07355886
Heavy Atom Count:19
Complexity:386

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2C=C(CC(=O)O)C(=O)O

Technology Process of 2-[(Naphthalen-1-yl)methylidene]butanedioic acid

There total 1 articles about 2-[(Naphthalen-1-yl)methylidene]butanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 107-93-7
(E)-but-2-enoic acid

: 103632-74-2,125702-08-1,17917-21-4
(1-naphthalenylmethylene)butanedioic acid

Guidance literature:

Reference yield:

: 103632-74-2,125702-08-1,17917-21-4
(1-naphthalenylmethylene)butanedioic acid

: 128318-33-2
(R)-4-Morpholin-4-yl-2-naphthalen-1-ylmethyl-4-oxo-butyric acid 4-nitro-phenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / (+)-BPPM-RhClO₄ / benzene; ethanol / 20 h / 3800 Torr / Ambient temperature

2: SOCl₂, DMF / 1 h / 80 °C

3: Et₃N / CH₂Cl₂ / 8 h / Ambient temperature

4: 97 percent / dimethylformamide / 3 h / 0 °C

With thionyl chloride; hydrogen; triethylamine; N,N-dimethyl-formamide; (+)-BPPM-RhClO₄; In ethanol; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1016/S0040-4039(00)94685-9

Reference yield:

: 103632-74-2,125702-08-1,17917-21-4
(1-naphthalenylmethylene)butanedioic acid

: 128318-43-4
di-4-nitrophenyl (R)-(1-naphthylmethyl)succinate

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / (+)-BPPM-RhClO₄ / benzene; ethanol / 20 h / 3800 Torr / Ambient temperature

2: SOCl₂, DMF / 1 h / 80 °C

3: Et₃N / CH₂Cl₂ / 8 h / Ambient temperature

With thionyl chloride; hydrogen; triethylamine; N,N-dimethyl-formamide; (+)-BPPM-RhClO₄; In ethanol; dichloromethane; benzene;
DOI:10.1016/S0040-4039(00)94685-9