Phenol, 2-[(4-methylphenyl)sulfonyl]-

Base Information

• Chemical Name: Phenol, 2-[(4-methylphenyl)sulfonyl]-
• CAS No.: 10371-01-4
• Molecular Formula: C13H12O3S
• Molecular Weight: 248.302
• DSSTox Substance ID: DTXSID80446907
• Nikkaji Number: J908.936E
• Wikidata: Q82265653
• Mol file: 10371-01-4.mol

Synonyms:Phenol, 2-[(4-methylphenyl)sulfonyl]-;2-(4-methylphenyl)sulfonylphenol;10371-01-4;2-Tosylphenol;SCHEMBL313277;2-hydroxyphenyl p-tolyl sulphone;DTXSID80446907;AKOS038554806

Chemical Property of Phenol, 2-[(4-methylphenyl)sulfonyl]-

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 248.05071541
• Heavy Atom Count: 17
• Complexity: 336

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2O

Technology Process of Phenol, 2-[(4-methylphenyl)sulfonyl]-

There total 16 articles about Phenol, 2-[(4-methylphenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

toluene-4-sulfonic acid phenyl ester (640-60-8) → 4-tosylphenol (7402-77-9) + 2-[(4-methylphenyl)sulfonyl]phenol (10371-01-4)

Guidance literature:

With aluminium trichloride; for 0.0166667h; Irradiation;

Reference yield:

→ 4-tosylphenol (7402-77-9) + 2-[(4-methylphenyl)sulfonyl]phenol (10371-01-4)

Guidance literature:

With carbon disulfide; aluminium trichloride; at 130 - 140 ℃;

Reference yield:

toluene-4-sulfonic acid phenyl ester (640-60-8) → 4-tosylphenol (7402-77-9) + 2-[(4-methylphenyl)sulfonyl]phenol (10371-01-4) + phenol (108-95-2,27073-41-2)

Guidance literature:

With fipronilβ-cyclodextrin; In methanol; for 0.5h; Product distribution; Irradiation; var. solvents, also phenyl benzenesulphonate;

upstream raw materials:

2'-methoxy-4-methyl-diphenylsulfone

toluene-4-sulfonic acid phenyl ester

2-Chloronitrobenzene

sodium 4-methylbenzenesulfinate

Downstream raw materials:

2'-methoxy-4-methyl-diphenylsulfone