3-Hydroxy-4-(1-naphthyloxy)butyronitrile

Base Information

Chemical Name:3-Hydroxy-4-(1-naphthyloxy)butyronitrile
CAS No.:20804-76-6
Molecular Formula:C14H13NO2
Molecular Weight:227.263
Hs Code.:2926909090
European Community (EC) Number:244-048-2
DSSTox Substance ID:DTXSID80943027
Nikkaji Number:J225.337B
Mol file:20804-76-6.mol

Synonyms:20804-76-6;3-Hydroxy-4-(1-naphthyloxy)butyronitrile;3-hydroxy-4-naphthalen-1-yloxybutanenitrile;EINECS 244-048-2;3-HYDROXY-4-(NAPHTHALEN-1-YLOXY)BUTANENITRILE;DTXSID80943027;3-Hydroxy-4-(1-naphthyloxy)butanenitrile;3-Hydroxy-4-[(naphthalen-1-yl)oxy]butanenitrile

Suppliers and Price of 3-Hydroxy-4-(1-naphthyloxy)butyronitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Hydroxy-4-(1-naphthyloxy)-butanenitrile
1g
$ 1525.00

TRC
3-Hydroxy-4-(1-naphthyloxy)-butanenitrile
250mg
$ 445.00

Total 5 raw suppliers

Chemical Property of 3-Hydroxy-4-(1-naphthyloxy)butyronitrile

Chemical Property:

Vapor Pressure:1.61E-09mmHg at 25°C
Boiling Point:467°C at 760 mmHg
Flash Point:236.2°C
PSA：53.25000
Density:1.206g/cm³
LogP:2.49318
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:227.094628657
Heavy Atom Count:17
Complexity:283

Purity/Quality:

99% ^*data from raw suppliers

3-Hydroxy-4-(1-naphthyloxy)-butanenitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2OCC(CC#N)O
Uses 3-Hydroxy-4-(1-naphthyloxy)-butanenitrile is an intermediate in the synthesis of Nadoxolol (N201040), which is a beta-adrenergic receptor blocker.

Technology Process of 3-Hydroxy-4-(1-naphthyloxy)butyronitrile

There total 3 articles about 3-Hydroxy-4-(1-naphthyloxy)butyronitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 2461-42-9
3-(1-naphthyloxy)-1,2-epoxypropane

: 143-33-9,25596-52-5
sodium cyanide

: 20804-76-6
3-hydroxy-4-(1-naphthyloxy)butanenitrile

Guidance literature:: With ammonium chloride; In methanol; water; at 85 ℃; for 15h;
DOI:10.1002/1615-4169(200108)343:6/7<726::aid-adsc726>3.3.co;2-5