1-[2-(2-Hydroxy-5-methoxyphenyl)-1,3-benzothiazol-3(2H)-yl]ethan-1-one

Base Information

Chemical Name:1-[2-(2-Hydroxy-5-methoxyphenyl)-1,3-benzothiazol-3(2H)-yl]ethan-1-one
CAS No.:105129-60-0
Molecular Formula:C16H15NO3S
Molecular Weight:301.366
Hs Code.:
DSSTox Substance ID:DTXSID70537277
Mol file:105129-60-0.mol

Synonyms:105129-60-0;SCHEMBL4345823;DTXSID70537277;1-[2-(2-Hydroxy-5-methoxyphenyl)-1,3-benzothiazol-3(2H)-yl]ethan-1-one

Suppliers and Price of 1-[2-(2-Hydroxy-5-methoxyphenyl)-1,3-benzothiazol-3(2H)-yl]ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[2-(2-Hydroxy-5-methoxyphenyl)-1,3-benzothiazol-3(2H)-yl]ethan-1-one

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:301.07726451
Heavy Atom Count:21
Complexity:392

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1C(SC2=CC=CC=C21)C3=C(C=CC(=C3)OC)O

Technology Process of 1-[2-(2-Hydroxy-5-methoxyphenyl)-1,3-benzothiazol-3(2H)-yl]ethan-1-one

There total 5 articles about 1-[2-(2-Hydroxy-5-methoxyphenyl)-1,3-benzothiazol-3(2H)-yl]ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 108-24-7
acetic anhydride

: 41570-02-9
2-(2,3-dihydrobenzo[d]thiazol-2-yl)-4-methoxyphenol

: 105129-60-0
3-acetyl-2-(2-hydroxy-5-methoxyphenyl)benzothiazoline

Guidance literature:: for 4h; Ambient temperature;
DOI:10.1021/jm00400a006

Reference yield: 77.0%

: 105129-60-0
3-acetyl-2-(2-hydroxy-5-methoxyphenyl)benzothiazoline

Guidance literature:

Reference yield:

: 672-13-9
2-hydroxy-5-methoxybenzaldehyde

: 105129-60-0
3-acetyl-2-(2-hydroxy-5-methoxyphenyl)benzothiazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / methanol / 1.) room temperature, 1 h, 2.) 0 deg C, 1 h

2: 96 percent / 4 h / Ambient temperature

In methanol;
DOI:10.1021/jm00400a006