(4-Fluoro-3-(trifluoromethyl)phenyl)hydrazine

Base Information

• Chemical Name: (4-Fluoro-3-(trifluoromethyl)phenyl)hydrazine
• CAS No.: 105224-02-0
• Molecular Formula: C7H6F4N2
• Molecular Weight: 194.132
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID90379232
• Wikidata: Q82168949
• Mol file: 105224-02-0.mol

Synonyms:105224-02-0;(4-fluoro-3-(trifluoromethyl)phenyl)hydrazine;[4-fluoro-3-(trifluoromethyl)phenyl]hydrazine;(4-Fluoro-3-trifluoromethyl-phenyl)-hydrazine;4-FLUORO-3-(TRIFLUOROMETHYL)PHENYLHYDRAZINE;(4-fluoro-3-trifluoromethyl)phenyl hydrazine;Hydrazine, [4-fluoro-3-(trifluoromethyl)phenyl]-;SCHEMBL3529272;DTXSID90379232;AKOS009157832;SB30400;4-fluoro-3-trifluoromethyl phenyl hydrazine;CS-0000083;EN300-271023;1-(4-fluoro-3-(trifluoromethyl)phenyl)hydrazine

Chemical Property of (4-Fluoro-3-(trifluoromethyl)phenyl)hydrazine

Chemical Property:

• PSA: 38.05000
• LogP: 2.90340
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 194.04671085
• Heavy Atom Count: 13
• Complexity: 170

Purity/Quality:

97% ^*data from raw suppliers

[4-Fluoro-3-(trifluoromethyl)phenyl]hydrazine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1NN)C(F)(F)F)F

Technology Process of (4-Fluoro-3-(trifluoromethyl)phenyl)hydrazine

There total 2 articles about (4-Fluoro-3-(trifluoromethyl)phenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Fluoro-3-trifluoromethylaniline (2357-47-3) → 1-(4-fluoro-3-(trifluoromethyl)phenyl)hydrazine (105224-02-0)

Guidance literature:

4-Fluoro-3-trifluoromethylaniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.5h;

With hydrogenchloride; tin(II) chloride dihdyrate; In water; at 80 ℃;

Reference yield:

→ 4-hydrazinobenzonitrile (17672-27-4) + 1-(4-fluoro-3-(trifluoromethyl)phenyl)hydrazine (105224-02-0)

Guidance literature:

Reference yield:

2,3-dibromopropionitrile (4554-16-9) + 1-(4-fluoro-3-(trifluoromethyl)phenyl)hydrazine (105224-02-0) → 1-(4-fluoro-3-trifluoromethyl-phenyl)-1H-pyrazol-3-ylamine

Guidance literature:

1-(4-fluoro-3-(trifluoromethyl)phenyl)hydrazine; With potassium tert-butylate; In tert-butyl alcohol; for 0.0833333h;

2,3-dibromopropionitrile; In tert-butyl alcohol; for 3h; Heating / reflux;

upstream raw materials:

4-Fluoro-3-trifluoromethylaniline