Hex-5-en-2-amine

Base Information

• Chemical Name: Hex-5-en-2-amine
• CAS No.: 7380-76-9
• Molecular Formula: C₆H₁₃N
• Molecular Weight: 99.1759
• DSSTox Substance ID: DTXSID60994779
• Nikkaji Number: J49.974I
• Mol file: 7380-76-9.mol

Synonyms:hex-5-en-2-amine;7380-76-9;1-Methyl-4-pentenylamine;4-Pentenylamine, 1-methyl-;1-Hexene-5-amine;BRN 1736119;0-04-00-00223 (Beilstein Handbook Reference);1-methyl-4-pentene-1-amine;5-Hexen-2-amine;starbld0039764;1-Methyl-pent-4-enylamine;DTXSID60994779;AKOS006347650;LS-102215;EN300-1251668;A1-02026;F8883-6520;73604-43-0

Chemical Property of Hex-5-en-2-amine

Chemical Property:

• Vapor Pressure: 18.6mmHg at 25°C
• Boiling Point: 116°C at 760 mmHg
• PKA: 10.67±0.35(Predicted)
• Flash Point: 17.5°C
• Density: 0.782g/cm³
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 99.104799419
• Heavy Atom Count: 7
• Complexity: 50.1

Purity/Quality:

95% ^*data from raw suppliers

1-Methyl-pent-4-enylamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CCC=C)N
• Uses: Hex-5-en-2-amine can be used in a method for making opaque colored silicone hydrogel contact lenses.

Technology Process of Hex-5-en-2-amine

There total 6 articles about Hex-5-en-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

hex-5-en-2-one oxime (59239-06-4) → 2-aminohex-5-ene (7380-76-9,73604-43-0)

Guidance literature:

hex-5-en-2-one oxime; With lithium aluminium tetrahydride; In diethyl ether; for 3h; Heating;

With sodium hydroxide; water; In diethyl ether; at 20 ℃; for 2h;

DOI:10.1021/ol051574h

Reference yield:

5-Hexen-2-one (109-49-9) → 2-aminohex-5-ene (7380-76-9,73604-43-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / NH₂OH*HCl, pyridine / ethanol / 1 h / Heating

2: 57 percent / Na, EtOH

With pyridine; ethanol; hydroxylamine hydrochloride; sodium; In ethanol;

DOI:10.1055/s-1999-2640

Reference yield:

→ 2-aminohex-5-ene (7380-76-9,73604-43-0)

Guidance literature:

With ethanol; sodium;

upstream raw materials:

hex-5-en-2-one oxime

ethanol

pentan-1-ol

5-Hexen-2-one

Downstream raw materials:

(+/-)-tert-butyl hex-5-en-2-ylcarbamate

2,5-dimethylpyrrolide

2-amino-4-hexene

N-methyl-1-methylpent-4-enylamine