N(6)-((dimethylamino)methylene)mitomycin C

Base Information

Chemical Name:N(6)-((dimethylamino)methylene)mitomycin C
CAS No.:88949-01-3
Molecular Formula:C18H23 N5 O5
Molecular Weight:389.411
Hs Code.:
UNII:B9W6OO9209
DSSTox Substance ID:DTXSID701098663
Nikkaji Number:J425.723E
Mol file:88949-01-3.mol

Synonyms:BMY 25282;BMY-25282;DMA-MMC;N(6)-((dimethylamino)methylene)mitomycin C

Suppliers and Price of N(6)-((dimethylamino)methylene)mitomycin C

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N(6)-((dimethylamino)methylene)mitomycin C

Chemical Property:

PSA：137.46000
LogP:-0.23950
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:389.16991885
Heavy Atom Count:28
Complexity:876

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N=CN(C)C
Isomeric SMILES:CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N=CN(C)C

Technology Process of N(6)-((dimethylamino)methylene)mitomycin C

There total 1 articles about N(6)-((dimethylamino)methylene)mitomycin C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 88948-91-8
7-<<(dimethylamino)methylene>amino>-N¹⁰-<(dimethylamino)methylene>-9a-methoxymitosane

: 91-00-9
Benzhydrylamine

: 50-07-7
mitomycin C

: 88949-01-3
7-<<(dimethylamino)methylene>amino>-9a-methoxymitosane

: 110971-78-3
7-<(diphenylmethyl)amino>-9a-methoxymitosane

Guidance literature:: In methanol; at 54 ℃; for 4h;
DOI:10.1021/jo00234a017

Reference yield: 66.0%

: 2687-43-6
O-benzylhydoxylamine hydrochloride

: 88949-01-3
7-<<(dimethylamino)methylene>amino>-9a-methoxymitosane

: 88949-13-7
7-<<<(benzyloxy)amino>methylene>amino>-9a-methoxymitosane

Guidance literature:: With triethylamine; In methanol; for 2.5h; Ambient temperature;
DOI:10.1021/jo00234a017

Reference yield:

: 88949-01-3
7-<<(dimethylamino)methylene>amino>-9a-methoxymitosane

: 50-07-7
mitomycin C

Guidance literature:: With phsphate buffer; In water; at 45 ℃; Rate constant; Mechanism; pH 6.5, other pH, other buffer, other temperature;
DOI:10.1002/jps.2600750223