N-[2-(5,6-Diphenyl-1,2,4-triazin-3-yl)phenyl]-2,2,2-trifluoroacetamide

Base Information

Chemical Name:N-[2-(5,6-Diphenyl-1,2,4-triazin-3-yl)phenyl]-2,2,2-trifluoroacetamide
CAS No.:106823-31-8
Molecular Formula:C23H15F3N4O
Molecular Weight:420.394
Hs Code.:
DSSTox Substance ID:DTXSID70545170
Wikidata:Q82422577
Mol file:106823-31-8.mol

Synonyms:106823-31-8;N-[2-(5,6-Diphenyl-1,2,4-triazin-3-yl)phenyl]-2,2,2-trifluoroacetamide;DTXSID70545170

Suppliers and Price of N-[2-(5,6-Diphenyl-1,2,4-triazin-3-yl)phenyl]-2,2,2-trifluoroacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(5,6-Diphenyl-1,2,4-triazin-3-yl)phenyl]-2,2,2-trifluoroacetamide

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:420.11979560
Heavy Atom Count:31
Complexity:590

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(N=NC(=N2)C3=CC=CC=C3NC(=O)C(F)(F)F)C4=CC=CC=C4

Technology Process of N-[2-(5,6-Diphenyl-1,2,4-triazin-3-yl)phenyl]-2,2,2-trifluoroacetamide

There total 1 articles about N-[2-(5,6-Diphenyl-1,2,4-triazin-3-yl)phenyl]-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 407-25-0
trifluoroacetic anhydride

: 89213-58-1
5,6-diphenyl-3-(2'-aminophenyl)-1,2,4-triazine

: 106823-31-8
5,6-diphenyl-3-<2'-(trifluoroacetamido)phenyl>-1,2,4-triazine

Guidance literature:: In diethyl ether; for 0.5h; Ambient temperature;
DOI:10.1021/jo00267a006

Reference yield: 21.0%

: 106823-31-8
5,6-diphenyl-3-<2'-(trifluoroacetamido)phenyl>-1,2,4-triazine

: 590-17-0
cyanomethyl bromide

: 118207-17-3
3-<2'-<(cyanomethyl)amino>phenyl>-5,6-diphenyl-1,2,4-triazine

: 106823-33-0
3-<2'-phenyl>-5,6-diphenyl-1,2,4-triazine

Guidance literature:: With potassium hydroxide; In acetone; for 0.166667h; Heating;
DOI:10.1021/jo00267a006

Reference yield:

: 106823-31-8
5,6-diphenyl-3-<2'-(trifluoroacetamido)phenyl>-1,2,4-triazine

: 106823-35-2
2,3-diphenylpyrazino<2,3-c>quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 21 percent / KOH / acetone / 0.17 h / Heating

2: diethyl ether

3: 47 percent / diphenyl ether / 2 h / Heating

With potassium hydroxide; In diphenylether; diethyl ether; acetone;
DOI:10.1021/jo00267a006