Benzenemethanol, a-(1-azabicyclo[2.2.2]oct-2-ylethynyl)-a-phenyl-

Base Information

Chemical Name:Benzenemethanol, a-(1-azabicyclo[2.2.2]oct-2-ylethynyl)-a-phenyl-
CAS No.:106824-70-8
Molecular Formula:C₂₂H₂₃NO
Molecular Weight:317.431
Hs Code.:
Mol file:106824-70-8.mol

Synonyms:3-(1-Aza-bicyclo[2.2.2]oct-2-yl)-1,1-diphenyl-prop-2-yn-1-ol;

Suppliers and Price of Benzenemethanol, a-(1-azabicyclo[2.2.2]oct-2-ylethynyl)-a-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenemethanol, a-(1-azabicyclo[2.2.2]oct-2-ylethynyl)-a-phenyl-

Chemical Property:

PSA：23.47000
LogP:3.34810

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenemethanol, a-(1-azabicyclo[2.2.2]oct-2-ylethynyl)-a-phenyl-

There total 3 articles about Benzenemethanol, a-(1-azabicyclo[2.2.2]oct-2-ylethynyl)-a-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106824-75-3
2-Acetylquinuclidine

: 106824-70-8
2-(3',3'-Diphenyl-3'-oxy-1'-propinyl)quinuclidine

Guidance literature:: Multi-step reaction with 3 steps

1: PCl₅ / POCl₃

2: NaNH₂, NH₃

3: 1.) NaNH₂ / 1.) ether, liq. NH₃, 15 min, 2.) ether, reflux, 2 h

With phosphorus pentachloride; ammonia; sodium amide; In trichlorophosphate;
DOI:10.1007/BF00763694

Reference yield:

: 106824-76-4
2-(1-Chloro-vinyl)-1-aza-bicyclo[2.2.2]octane

: 106824-70-8
2-(3',3'-Diphenyl-3'-oxy-1'-propinyl)quinuclidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaNH₂, NH₃

2: 1.) NaNH₂ / 1.) ether, liq. NH₃, 15 min, 2.) ether, reflux, 2 h

With ammonia; sodium amide;
DOI:10.1007/BF00763694

Reference yield:

: 119-61-9
benzophenone

: 106824-77-5
2-Ethynylquinuclidine

: 106824-70-8
2-(3',3'-Diphenyl-3'-oxy-1'-propinyl)quinuclidine

Guidance literature:: With sodium amide; Yield given. Multistep reaction; 1.) ether, liq. NH₃, 15 min, 2.) ether, reflux, 2 h;
DOI:10.1007/BF00763694