Uridine, 2'-deoxy-5-[4-(dimethylamino)phenyl]-

Base Information

• Chemical Name: Uridine, 2'-deoxy-5-[4-(dimethylamino)phenyl]-
• CAS No.: 108664-86-4
• Molecular Formula: C₁₇H₂₁N₃O₅
• Molecular Weight: 347.371
• Mol file: 108664-86-4.mol

Synonyms:5-[p-(N,N-dimethylamino)phenyl]-2'-deoxyuridine;5-(4-Dimethylamino-phenyl)-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione;

Chemical Property of Uridine, 2'-deoxy-5-[4-(dimethylamino)phenyl]-

Chemical Property:

• PSA: 107.79000
• LogP: -0.08970

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Uridine, 2'-deoxy-5-[4-(dimethylamino)phenyl]-

There total 1 articles about Uridine, 2'-deoxy-5-[4-(dimethylamino)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 5-(p-aminophenyl)-2'-deoxyuridine (108664-87-5) → 5--2'-deoxyuridine (108664-86-4)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; water; acetonitrile; for 12h; Yield given;

DOI:10.1021/jo00392a023

Reference yield:

5--2'-deoxyuridine (108664-86-4) → C17H20N3O8P(2-) (113997-13-0)

Guidance literature:

With trimethyl phosphite; trichlorophosphate; at 0 ℃; for 8h;

DOI:10.1021/jm00401a013

upstream raw materials:

formaldehyd

5-(p-aminophenyl)-2'-deoxyuridine

Downstream raw materials:

C₁₇H₂₀N₃O₈P^(2-)