4-[(Methanesulfonyl)methyl]-1-(4-methylbenzene-1-sulfonyl)-1H-indole

Base Information

Chemical Name:4-[(Methanesulfonyl)methyl]-1-(4-methylbenzene-1-sulfonyl)-1H-indole
CAS No.:108861-48-9
Molecular Formula:C17H17NO4S2
Molecular Weight:363.458
Hs Code.:
DSSTox Substance ID:DTXSID10554286
Wikidata:Q82435225
Mol file:108861-48-9.mol

Synonyms:108861-48-9;DTXSID10554286;4-[(Methanesulfonyl)methyl]-1-(4-methylbenzene-1-sulfonyl)-1H-indole

Suppliers and Price of 4-[(Methanesulfonyl)methyl]-1-(4-methylbenzene-1-sulfonyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[(Methanesulfonyl)methyl]-1-(4-methylbenzene-1-sulfonyl)-1H-indole

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:363.05990037
Heavy Atom Count:24
Complexity:639

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2C=CC3=C(C=CC=C32)CS(=O)(=O)C

Technology Process of 4-[(Methanesulfonyl)methyl]-1-(4-methylbenzene-1-sulfonyl)-1H-indole

There total 2 articles about 4-[(Methanesulfonyl)methyl]-1-(4-methylbenzene-1-sulfonyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.1%

: 113484-99-4
4-Methanesulfonylmethyl-1-(toluene-4-sulfonyl)-4,5,6,7-tetrahydro-1H-indol-4-ol

: 108861-48-9
4-Methanesulfonylmethyl-1-(toluene-4-sulfonyl)-1H-indole

Guidance literature:: With copper dichloride; In acetic acid; for 5h; Heating;
DOI:10.1016/S0040-4039(00)84745-0

Reference yield:

: 35577-89-0
1-[(4-methylbenzene)sulfonyl]-4,5,6,7-tetrahydro-1H-indol-4-one

: 108861-48-9
4-Methanesulfonylmethyl-1-(toluene-4-sulfonyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) butyllithium / 1.) THF, -78 deg C, 2h; 2.) from -78 deg C to 0 deg C, 4 h

2: 81.1 percent / CuCl₂ / aq. acetic acid / 5 h / Heating

With n-butyllithium; copper dichloride; In acetic acid;
DOI:10.1016/S0040-4039(00)84745-0