5-Chloro-2-(2-hydroxybenzylideneamino)benzophenone

Base Information

• Chemical Name: 5-Chloro-2-(2-hydroxybenzylideneamino)benzophenone
• CAS No.: 109881-51-8
• Molecular Formula: C₂₀H₁₄ClNO₂
• Molecular Weight: 335.79
• European Community (EC) Number: 666-344-4
• DSSTox Substance ID: DTXSID00425698
• Nikkaji Number: J1.018.258A
• Mol file: 109881-51-8.mol

Synonyms:5-CHLORO-2-(2-HYDROXYBENZYLIDENEAMINO)BENZOPHENONE;109881-51-8;6-[(2-benzoyl-4-chloroanilino)methylidene]cyclohexa-2,4-dien-1-one;Oprea1_622120;DTXSID00425698;AKOS001581796;EU-0067639;2-(2-hydroxybenzylidene)amino-5-chlorobenzophenone;2-[N-(2-benzoyl-4-chlorophenyl)carboximidoyl]phenol;2-[(E)-[(2-BENZOYL-4-CHLOROPHENYL)IMINO]METHYL]PHENOL;{5-Chloro-2-[(2-hydroxybenzylidene)amino]phenyl}(phenyl)methanone

Chemical Property of 5-Chloro-2-(2-hydroxybenzylideneamino)benzophenone

Chemical Property:

• PSA: 46.17000
• LogP: 4.63490
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 335.0713064
• Heavy Atom Count: 24
• Complexity: 447

Purity/Quality:

5-CHLORO-2-(2-HYDROXYBENZYLIDENEAMINO)BENZOPHENONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=C(C=CC(=C2)Cl)N=CC3=CC=CC=C3O

Technology Process of 5-Chloro-2-(2-hydroxybenzylideneamino)benzophenone

There total 2 articles about 5-Chloro-2-(2-hydroxybenzylideneamino)benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-methyl-benzyl alcohol (89-95-2) + 5-chloro-2-aminobenzophenone (719-59-5) → 2-{[(5-chlorobenzophenon-2-yl)imino]methyl}-phenol (109881-51-8)

Guidance literature:

at 20 ℃; for 0.05h; microwave irradiation;

DOI:10.1081/SCC-120006012

Reference yield: 87.0%

salicylaldehyde (90-02-8) + 5-chloro-2-aminobenzophenone (719-59-5) → 2-{[(5-chlorobenzophenon-2-yl)imino]methyl}-phenol (109881-51-8)

Guidance literature:

In benzene; for 1h; Heating;

Reference yield:

2-{[(5-chlorobenzophenon-2-yl)imino]methyl}-phenol (109881-51-8) + cobalt(II) chloride (7646-79-9,14543-09-0,16413-89-1) → Co(C20H13NO2Cl2) (109896-67-5)

Guidance literature:

With NaOH; In ethanol; dissolving the ligand (1 mol) in absolute ethanol containing 1 mol of NaOH; addn. of an ethanolic soln. of CoCl2 (1 mol); refluxing for 2 h under anhydrous conditions; pptn.; filtn., washing with absolute ethanol; drying; elem. anal.;

upstream raw materials:

salicylaldehyde

5-chloro-2-aminobenzophenone

2-methyl-benzyl alcohol

Downstream raw materials:

Cu(C₂₀H₁₃NO₂Cl₂)

Co(C₂₀H₁₃NO₂Cl₂)

Hg(C₂₀H₁₃NO₂Cl₂)

Ni(C₂₀H₁₃NO₂Cl₂)