4-Methyl-1-phenylquinolin-2(1h)-one

Base Information

• Chemical Name: 4-Methyl-1-phenylquinolin-2(1h)-one
• CAS No.: 2540-30-9
• Molecular Formula: C16H13 N O
• Molecular Weight: 235.285
• Hs Code.: 2933790090
• European Community (EC) Number: 621-189-1
• NSC Number: 109782
• DSSTox Substance ID: DTXSID10296533
• Wikidata: Q82037175
• Mol file: 2540-30-9.mol

Synonyms:4-methyl-1-phenylquinolin-2(1h)-one;2540-30-9;4-methyl-1-phenylquinolin-2-one;MFCD00024050;2(1H)-Quinolinone, 4-methyl-1-phenyl-;4-methyl-1-phenyl-quinolin-2-one;NSC109782;4-methyl-1-phenyl-1,2-dihydroquinolin-2-one;4-Methyl-1-Phenylquinolinone;SCHEMBL378029;DTXSID10296533;ILKUVYJZEPVFHW-UHFFFAOYSA-N;AMY41316;CAA54030;CS1023;AKOS022175025;DS-7540;NSC-109782;SB71592;SY100676;1,2-dihydro-4-methyl-1-phenyl-2-quinolone;4-METHYL-1-PHENYL-2(1H)-QUINOLONE;CS-0153127;FT-0727531;1,2-dihydro-4-methyl-2-oxo-1-phenylquinoline;A877595

Chemical Property of 4-Methyl-1-phenylquinolin-2(1h)-one

Chemical Property:

• Vapor Pressure: 3.64E-06mmHg at 25°C
• Melting Point: 134-135 °C
• Boiling Point: 386°Cat760mmHg
• PKA: -3.47±0.40(Predicted)
• Flash Point: 179.6°C
• PSA: 22.00000
• Density: 1.18g/cm³
• LogP: 3.29910
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 235.099714038
• Heavy Atom Count: 18
• Complexity: 354

Purity/Quality:

98%, ^*data from raw suppliers

4-Methyl-1-phenylquinolin-2(1H)-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=O)N(C2=CC=CC=C12)C3=CC=CC=C3

Technology Process of 4-Methyl-1-phenylquinolin-2(1h)-one

There total 13 articles about 4-Methyl-1-phenylquinolin-2(1h)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-methyl-1,2-dihydroquinolin-2-one (607-66-9) + Diphenyliodonium triflate (66003-76-7) → 1,2-dihydro-4-methyl-1-phenyl-2-quinolone (2540-30-9)

Guidance literature:

With sodium hydroxide; In water; at 80 ℃; for 0.5h; Microwave irradiation;

DOI:10.1039/c7ob00940b

Reference yield: 65.0%

2-butenoic acid (3724-65-0) + diphenylamine (122-39-4) → 1,2-dihydro-4-methyl-1-phenyl-2-quinolone (2540-30-9)

Guidance literature:

With 1,10-Phenanthroline; palladium(II) trimethylacetate; copper diacetate; trifluoroacetic acid; In methanol; at 110 ℃; for 24h;

DOI:10.1002/chem.201500774

Reference yield: 60.0%

(E)-N-phenyl-3-phenylbut-2-enamide (21298-82-8) → 1,2-dihydro-4-methyl-1-phenyl-2-quinolone (2540-30-9)

Guidance literature:

With Ir(dF(CF₃)ppy)2(bpy)PF₆; tributylmethylammonium dibutyl phosphate; In 1,2-dichloro-ethane; at 60 ℃; Sealed tube; Irradiation;

DOI:10.1021/acs.orglett.7b03600

upstream raw materials:

N,N-diphenylacetoacetamide

2-acetyl-3-oxo-butyric acid diphenylamide

sulfuric acid

N,N-diphenylacetamide

Downstream raw materials:

C₂₇H₂₆N₃O⁽¹⁺⁾*I^(1-)

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 2540-30-9 4-Methyl-1-phenylquinolin-2(1H)-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send