Bis(4-nitrophenyl) sulfone

Base Information

• Chemical Name: Bis(4-nitrophenyl) sulfone
• CAS No.: 1156-50-9
• Molecular Formula: C12H8 N2 O6 S
• Molecular Weight: 308.271
• Hs Code.: 2904909090
• European Community (EC) Number: 214-589-9
• NSC Number: 20609
• DSSTox Substance ID: DTXSID60151143
• Nikkaji Number: J168.818I
• Wikidata: Q83017547
• ChEMBL ID: CHEMBL215397
• Mol file: 1156-50-9.mol

Synonyms:Bis(4-nitrophenyl) sulfone;1156-50-9;4-Nitrophenyl sulfone;Bis(4-nitrophenyl)sulfone;Bis(4-nitrophenyl) sulphone;4,4'-Dinitrodiphenyl sulfone;1-nitro-4-(4-nitrophenyl)sulfonylbenzene;Bis(p-nitrophenyl) sulfone;4,4'-Dinitrodiphenylsulfone;1,1'-Sulfonylbis(4-nitrobenzene);EINECS 214-589-9;NSC 20609;Benzene, 1,1'-sulfonylbis(4-nitro-;Benzene, 1,1'-sulfonylbis[4-nitro-;BRN 2060993;Sulfone, bis(p-nitrophenyl);4,4'-sulfonylbis(nitrobenzene);NSC20609;NSC-20609;1-nitro-4-(4-nitrobenzenesulfonyl)benzene;Benzene, 1,1'-sulfonylbis(4-nitro- (9CI);4-06-00-01698 (Beilstein Handbook Reference);Dextro camphorquinone;1-nitro-4-[(4-nitrobenzene)sulfonyl]benzene;4-NITRO-PHENYL-SULFONE;CHEMBL215397;SCHEMBL3158508;BDBM11302;DTXSID60151143;MFCD00010447;AKOS001038366;1-nitro-4-(4-nitrophenyl)sulfonyl-benzene;LS-147976;CS-0441411;FT-0633413;D89946;EN300-7406653;J-003313;Z56888745

Chemical Property of Bis(4-nitrophenyl) sulfone

Chemical Property:

• Vapor Pressure: 3.18E-11mmHg at 25°C
• Melting Point: 178-185oC
• Boiling Point: 541.1°C at 760 mmHg
• Flash Point: 281°C
• PSA: 134.16000
• Density: 1.53g/cm³
• LogP: 4.46300
• Storage Temp.: Refrigerator
• Solubility.: Acetonitrile (Slightly), DMSO (Slightly)
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 308.01030715
• Heavy Atom Count: 21
• Complexity: 447

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(4-nitrophenyl) Sulfone ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22
• Safety Statements: 22-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of Bis(4-nitrophenyl) sulfone

There total 15 articles about Bis(4-nitrophenyl) sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

bis(4-nitrophenyl)sulfide (1223-31-0) → 4-nitrophenyl sulfone (1156-50-9)

Guidance literature:

With dihydrogen peroxide; methyltrioxorhenium(VII); In ethanol; at 50 ℃; for 8h;

DOI:10.1246/bcsj.69.2955

Reference yield: 95.0%

→ 4-nitrophenyl sulfone (1156-50-9)

Guidance literature:

With 2C₂H₃O₂^(1-)*C₂₆H₃₀B₁₀P₂*Cu⁽²⁺⁾; In toluene; at 20 ℃; for 3h;

Reference yield: 10.0%

bis(4-nitrophenyl)sulfide (1223-31-0) → 4,4'-dinitrodiphenyl sulfoxide (1774-38-5) + 4-nitrophenyl sulfone (1156-50-9)

Guidance literature:

With dihydrogen peroxide; methyltrioxorhenium(VII); In ethanol; at 50 ℃; for 5h;

DOI:10.1246/bcsj.69.2955

upstream raw materials:

di(p-nitrophenyl) disulfide

bis(4-nitrophenyl)sulfide

4,4'-dinitrodiphenyl sulfoxide

2,2'-dinitrophenyl sulphoxide

Downstream raw materials:

acedapsone

4-(4-nitrophenylsulfonyl)aniline

dapsone dihydroxylamine

dapsone

Refernces

• 1、 Peng, Yao. "Synthesis of symmetrical diaryl sulfone by homocoupling of sodium arylsulfinate". . p. 265 - 268. Retrieved 2014.
• 2、 Ciocca,Canonica. "-". . p. 113,119. Retrieved 1946.
• 3、 -. "Synthetic method of diarylsulfone compound". Paragraph 0029; 0033-0036. . Retrieved 2020/10/04.
• 4、 -. "PROCESS FOR THE PREPARATION OF SULFONAMIDE COMPOUNDS". Paragraph 0047. . Retrieved 2014/10/16.