2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole

Base Information

Chemical Name:2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole
CAS No.:110319-95-4
Molecular Formula:C13H15NO3S
Molecular Weight:265.333
Hs Code.:
DSSTox Substance ID:DTXSID30552087
Wikidata:Q82432083
Mol file:110319-95-4.mol

Synonyms:110319-95-4;2-(5-(Ethylsulfonyl)-2-methoxyphenyl)-1H-pyrrole;2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole;SCHEMBL8544972;DTXSID30552087;CDDVVZUJMPHDEG-UHFFFAOYSA-N;2-(2-methoxy-5-ethylsulfonylphenyl)-1H-pyrrole;2-[5-(Ethanesulfonyl)-2-methoxyphenyl]-1H-pyrrole

Suppliers and Price of 2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:265.07726451
Heavy Atom Count:18
Complexity:363

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCS(=O)(=O)C1=CC(=C(C=C1)OC)C2=CC=CN2

Technology Process of 2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole

There total 4 articles about 2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20951-10-4
2-bromo-4-ethylsulfonyl-1-methoxybenzene

: 110319-95-4
2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / Na₂CO₃, H₂O / Pd(PPh₃)4 / 1,2-dimethoxy-ethane / 4 h / Heating

2: NaOMe / methanol / Ambient temperature

With water; sodium methylate; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; 1,2-dimethoxyethane;
DOI:10.1055/s-1998-1834

Reference yield:

: 4-(5-Ethanesulfonyl-2-methoxy-phenyl)-4-oxo-butyraldehyde

: 110319-95-4
2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole

Guidance literature:: With ammonium acetate; In ethanol; for 1.5h; Yield given; Heating;

Reference yield:

: 23694-16-8
5-Ethylsulfonyl-2-methoxybenzoyl chloride

: 110319-95-4
2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Mg, 2.) cuprous bromide / 1.) THF, 30 deg C, 30 min, 2.) THF, a) -70 deg C, 30 min, b) 15 deg C, 1 h

2: 2N HCl / 16 h

3: ammonium acetate / ethanol / 1.5 h / Heating

With ammonium acetate; hydrogenchloride; magnesium; copper(I) bromide; In ethanol;