3,5-Pyridinedicarboxylic acid, 2-[[(2-aminoethyl)thio]methyl]-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, diethyl ester

Base Information

Chemical Name:3,5-Pyridinedicarboxylic acid, 2-[[(2-aminoethyl)thio]methyl]-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, diethyl ester
CAS No.:110646-16-7
Molecular Formula:C21H27N3O6S
Molecular Weight:449.528
Hs Code.:
Mol file:110646-16-7.mol

Synonyms:

Suppliers and Price of 3,5-Pyridinedicarboxylic acid, 2-[[(2-aminoethyl)thio]methyl]-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, diethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,5-Pyridinedicarboxylic acid, 2-[[(2-aminoethyl)thio]methyl]-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3,5-Pyridinedicarboxylic acid, 2-[[(2-aminoethyl)thio]methyl]-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, diethyl ester

There total 4 articles about 3,5-Pyridinedicarboxylic acid, 2-[[(2-aminoethyl)thio]methyl]-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 156-57-0
2-mercaptoethylamine hydrochloride

: 105435-14-1
2-chloromethyl-3,5-dicarboethoxy-4-(3-nitrophenyl)-6-methyl-1,4-dihydropyridine

: 110646-16-7
2-(2-aminoethylthiomethyl)-3,5-dicarboethoxy-4-(m-nitrophenyl)-6-methyl-1,4-dihydropyridine

Guidance literature:: With sodium hydroxide; In 1,2-dimethoxyethane; ethanol; water; at -15 ℃; for 0.25h;
DOI:10.1016/0223-5234(93)90038-G

Reference yield:

: 638-07-3
ethyl (2-chloroaceto)acetate

: 110646-16-7
2-(2-aminoethylthiomethyl)-3,5-dicarboethoxy-4-(m-nitrophenyl)-6-methyl-1,4-dihydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) benzylamine, acetic acid / 1.) 2-propanol, RT, 24 h, 2.) 2-propanol, RT, 24 h

2: 5M NaOH / H₂O; ethanol; 1,2-dimethoxy-ethane / 0.25 h / -15 °C

With sodium hydroxide; acetic acid; benzylamine; In 1,2-dimethoxyethane; ethanol; water;
DOI:10.1016/0223-5234(93)90038-G

Reference yield:

: 99-61-6
3-nitro-benzaldehyde

: 110646-16-7
2-(2-aminoethylthiomethyl)-3,5-dicarboethoxy-4-(m-nitrophenyl)-6-methyl-1,4-dihydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) benzylamine, acetic acid / 1.) 2-propanol, RT, 24 h, 2.) 2-propanol, RT, 24 h

2: 5M NaOH / H₂O; ethanol; 1,2-dimethoxy-ethane / 0.25 h / -15 °C

With sodium hydroxide; acetic acid; benzylamine; In 1,2-dimethoxyethane; ethanol; water;
DOI:10.1016/0223-5234(93)90038-G