N-[4-[2-(1H-Imidazol-1-yl)acetyl]phenyl]-N-(phenylmethyl)methanesulfonamide

Base Information

Chemical Name:N-[4-[2-(1H-Imidazol-1-yl)acetyl]phenyl]-N-(phenylmethyl)methanesulfonamide
CAS No.:110698-71-0
Molecular Formula:C19H19N3O3S
Molecular Weight:369.444
Hs Code.:
DSSTox Substance ID:DTXSID901143501
Mol file:110698-71-0.mol

Synonyms:DTXSID901143501;N-[4-[2-(1H-Imidazol-1-yl)acetyl]phenyl]-N-(phenylmethyl)methanesulfonamide;110698-71-0

Suppliers and Price of N-[4-[2-(1H-Imidazol-1-yl)acetyl]phenyl]-N-(phenylmethyl)methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-[2-(1H-Imidazol-1-yl)acetyl]phenyl]-N-(phenylmethyl)methanesulfonamide

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:369.11471265
Heavy Atom Count:26
Complexity:561

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)(=O)N(CC1=CC=CC=C1)C2=CC=C(C=C2)C(=O)CN3C=CN=C3

Technology Process of N-[4-[2-(1H-Imidazol-1-yl)acetyl]phenyl]-N-(phenylmethyl)methanesulfonamide

There total 3 articles about N-[4-[2-(1H-Imidazol-1-yl)acetyl]phenyl]-N-(phenylmethyl)methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 288-32-4
1H-imidazole

: 110698-62-9
N-<4-(2-bromo-1-oxoethyl)phenyl>-N-(phenylmethyl)methanesulfonamide

: 110698-71-0
N-<4-<2-(1H-imidazol-1-yl)-1-oxoethyl>phenyl>-N-(phenylmethyl)methanesulfonamide

Guidance literature:: In acetonitrile; 1.) 0 deg C, 2 h, 2.) RT, 15 h;
DOI:10.1021/jm00395a021

Reference yield:

: 100-39-0
benzyl bromide

: 110698-71-0
N-<4-<2-(1H-imidazol-1-yl)-1-oxoethyl>phenyl>-N-(phenylmethyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) sodium methoxide / 1.) methanol, RT, 30 min, 2.) methanol, RT, 28 h

2: 90.0 g / bromine / acetic acid / 17 h / Ambient temperature

3: 68 percent / acetonitrile / 1.) 0 deg C, 2 h, 2.) RT, 15 h

With bromine; sodium methylate; In acetic acid; acetonitrile;
DOI:10.1021/jm00395a021

Reference yield:

: 110698-70-9
N-<4-(1-oxoethyl)phenyl>-N-(phenylmethyl)methanesulfonamide

: 110698-71-0
N-<4-<2-(1H-imidazol-1-yl)-1-oxoethyl>phenyl>-N-(phenylmethyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 90.0 g / bromine / acetic acid / 17 h / Ambient temperature

2: 68 percent / acetonitrile / 1.) 0 deg C, 2 h, 2.) RT, 15 h

With bromine; In acetic acid; acetonitrile;
DOI:10.1021/jm00395a021