1-[(4-Chlorophenyl)methyl]-3-azetidinol

Base Information

Chemical Name:1-[(4-Chlorophenyl)methyl]-3-azetidinol
CAS No.:111043-50-6
Molecular Formula:C10H12ClNO
Molecular Weight:197.66100
Hs Code.:
DSSTox Substance ID:DTXSID101278716
Nikkaji Number:J583.091E

Synonyms:1-[(4-Chlorophenyl)methyl]-3-azetidinol;111043-50-6;1-(4-Chlorobenzyl)azetidin-3-ol;1-[(4-chlorophenyl)methyl]azetidin-3-ol;SCHEMBL2918814;DTXSID101278716;AKOS012391513;AB91988;CS-0363602;F1908-1875

Suppliers and Price of 1-[(4-Chlorophenyl)methyl]-3-azetidinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
1-[(4-Chlorophenyl)methyl]-3-azetidinol 97%
0.25g
$ 183.33

Acrotein
1-[(4-Chlorophenyl)methyl]-3-azetidinol 97%
1g
$ 412.50

Acrotein
1-[(4-Chlorophenyl)methyl]-3-azetidinol 97%
0.5g
$ 275.00

ACHEMBLOCK
1-[(4-Chlorophenyl)methyl]-3-azetidinol 95%
250MG
$ 220.00

Total 2 raw suppliers

Chemical Property of 1-[(4-Chlorophenyl)methyl]-3-azetidinol

Chemical Property:

PSA：23.47000
LogP:1.45440
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:197.0607417
Heavy Atom Count:13
Complexity:162

Purity/Quality:

99% ^*data from raw suppliers

1-[(4-Chlorophenyl)methyl]-3-azetidinol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CN1CC2=CC=C(C=C2)Cl)O
Uses 1-(4-Chlorobenzyl)-azetidine-3-ol is used in the synthesis of pharmaceutical compositions as antibacterial agents

Technology Process of 1-[(4-Chlorophenyl)methyl]-3-azetidinol

There total 5 articles about 1-[(4-Chlorophenyl)methyl]-3-azetidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 111043-44-8
1-(4-chlorobenzyl)-3-trimethylsilyloxy-azetidine

: 111043-50-6
1-(4-chlorobenzyl)-azetidine-3-ol

Guidance literature:: With hydrogenchloride; sodium hydroxide; In water; for 0.0833333h; Ambient temperature;

Reference yield: 42.0%

: 111043-50-6
1-(4-chlorobenzyl)-azetidine-3-ol

Guidance literature:

Reference yield:

: 104-86-9
4-chlorobenzylamine

: 111043-50-6
1-(4-chlorobenzyl)-azetidine-3-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 23 percent / triethylamine / acetonitrile / 72 h / Heating

2: 74 percent / 1.) conc. HCl; 2.) NaOH / H₂O / 0.08 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; triethylamine; In water; acetonitrile;