Benzyl (4-phenylbutyl)phosphonochloridate

Base Information

Chemical Name:Benzyl (4-phenylbutyl)phosphonochloridate
CAS No.:111496-24-3
Molecular Formula:C17H20ClO2P
Molecular Weight:322.771
Hs Code.:
DSSTox Substance ID:DTXSID10553012
Mol file:111496-24-3.mol

Synonyms:111496-24-3;Benzyl (4-phenylbutyl)phosphonochloridate;DTXSID10553012

Suppliers and Price of Benzyl (4-phenylbutyl)phosphonochloridate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzyl (4-phenylbutyl)phosphonochloridate

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:8
Exact Mass:322.0889446
Heavy Atom Count:21
Complexity:323

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCCCP(=O)(OCC2=CC=CC=C2)Cl

Technology Process of Benzyl (4-phenylbutyl)phosphonochloridate

There total 1 articles about Benzyl (4-phenylbutyl)phosphonochloridate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115947-38-1
dibenzyl 4-phenylbutylphosphonate

: 111496-24-3
C₁₇H₂₀ClO₂P

Guidance literature:: With phosphorus pentachloride; In benzene; for 2.5h; Heating;
DOI:10.1021/jm00396a033

Reference yield:

: 111496-24-3
C₁₇H₂₀ClO₂P

: (S)-1-{(S)-2-[Hydroxy-(4-phenyl-butyl)-phosphinoyloxy]-propionyl}-pyrrolidine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N, DMAP / CH₂Cl₂ / 1.) 0 deg C, 15 min, 2.) room temperature, 1 h

2: H₂, Et₃N / Pd-C / methanol / 3 h

With dmap; hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm00396a033

Reference yield:

: 89537-18-8
1-<(S)-2-hydroxy-1-oxopropyl>-L-proline phenylmethyl ester

: 111496-24-3
C₁₇H₂₀ClO₂P

: (S)-1-{(S)-2-[Benzyloxy-(4-phenyl-butyl)-phosphinoyloxy]-propionyl}-pyrrolidine-2-carboxylic acid benzyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; Yield given; 1.) 0 deg C, 15 min, 2.) room temperature, 1 h;
DOI:10.1021/jm00396a033