Acetic acid, (3-pentadecylphenoxy)-, hydrazide

Base Information

• Chemical Name: Acetic acid, (3-pentadecylphenoxy)-, hydrazide
• CAS No.: 117554-43-5
• Molecular Formula: C23H40 N2 O2
• Molecular Weight: 376.583
• DSSTox Substance ID: DTXSID10151810
• Wikidata: Q83018355
• Mol file: 117554-43-5.mol

Synonyms:(3-Pentadecylphenoxy)acetic acid hydrazide;Acetic acid, (3-pentadecylphenoxy)-, hydrazide;BRN 4202119;117554-43-5;DTXSID10151810

Chemical Property of Acetic acid, (3-pentadecylphenoxy)-, hydrazide

Chemical Property:

• Vapor Pressure: 7.73E-12mmHg at 25°C
• Boiling Point: 542.7°C at 760 mmHg
• Flash Point: 282°C
• Density: 0.973g/cm³
• XLogP3: 8.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 17
• Exact Mass: 376.308978523
• Heavy Atom Count: 27
• Complexity: 349

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC1=CC(=CC=C1)OCC(=O)NN

Technology Process of Acetic acid, (3-pentadecylphenoxy)-, hydrazide

There total 3 articles about Acetic acid, (3-pentadecylphenoxy)-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Methyl 3-pentadecylphenoxyacetate (117554-54-8) → 3-Pentadecylphenoxyacetic acid hydrazid (117554-43-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 5h; Heating;

Reference yield: 84.0%

ethyl-2-(3-pentadecylphenoxy)acetate (200133-85-3) → 3-Pentadecylphenoxyacetic acid hydrazid (117554-43-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 6h; Reflux;

DOI:10.3184/174751917X14925986241061

Reference yield:

3-n-Pentadecylphenol (501-24-6) → 3-Pentadecylphenoxyacetic acid hydrazid (117554-43-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 8 h

2: hydrazine hydrate / ethanol / 12 h / Reflux

With potassium carbonate; hydrazine hydrate; In ethanol; acetone;

DOI:10.1039/c5ra14744a

upstream raw materials:

Methyl 3-pentadecylphenoxyacetate

3-n-Pentadecylphenol

ethyl-2-(3-pentadecylphenoxy)acetate

Downstream raw materials:

2-Amino-5-(3'-pentadecylphenoxymethyl)-1,3,4-oxadiazole

(3-Pentadecyl-phenoxy)-acetic acid [1-phenyl-meth-(E)-ylidene]-hydrazide

(3-Pentadecyl-phenoxy)-acetic acid [1-(2,4-dichloro-phenyl)-meth-(E)-ylidene]-hydrazide

(3-Pentadecyl-phenoxy)-acetic acid [1-(3,4-dimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Refernces

• 1、 Behalo, Mohamed S.. "Facile Synthesis of Novel Amino Acids Derivatives as Potential Antibacterial Agents using Sustainable Materials". . p. 1181 - 1189. Retrieved 2017/09/13.
• 2、 Ramalingam, T.,Sattur, P. B.. "Synthesis and Biological Activity of 3-Pentadecylaryloxyacetic Acids, Their Hydrazides and Cyclic Derivatives: Oxadiazoles and Pyrroles". . p. 1204 - 1207. Retrieved 2007/10/02.