Columbamine chloride

Base Information

Chemical Name:Columbamine chloride
CAS No.:1916-10-5
Molecular Formula:C20H21NO4
Molecular Weight:373.836
Hs Code.:
ChEMBL ID:CHEMBL491511
DSSTox Substance ID:DTXSID10578785
NSC Number:209408

Synonyms:Columbamine chloride;1916-10-5;Columbamine (chloride);3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol;chloride;2-Hydroxy-3,9,10-trimethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium chloride;Columbamine hydrochloride;CHEMBL491511;SCHEMBL3324164;HY-N0926A;DTXSID10578785;NSC209408;AKOS030500956;NSC-209408;CS-0898361

Suppliers and Price of Columbamine chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of Columbamine chloride

Chemical Property:

Vapor Pressure:3.37E-17mmHg at 25°C
Boiling Point:644.3°C at 760 mmHg
Flash Point:343.5°C
Density:1.32g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:373.1080858
Heavy Atom Count:26
Complexity:461

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)O)OC.[Cl-]

Technology Process of Columbamine chloride

There total 1 articles about Columbamine chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 80-48-8
methyl p-toluene sulfonate

: 2,3-dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium chloride

: 1916-10-5
jatrorrhizine chloride

: 10605-02-4,947153-64-2
palmatine chloride

Guidance literature:: With potassium carbonate; In methanol; at 60 ℃; for 8h;
DOI:10.1016/j.neuint.2020.104807

Reference yield:

: 1916-10-5
jatrorrhizine chloride

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: C₂₈H₂₇N₂O₇S⁽¹⁺⁾*Cl^(1-)

Guidance literature:: jatrorrhizine chloride; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1.33333h; Cooling with ice;

p-acetylaminobenzenesulfonyl chloride; In N,N-dimethyl-formamide; at 20 ℃;