(Z)-3-(2-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-3-buten-2-one

Base Information

Chemical Name:(Z)-3-(2-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-3-buten-2-one
CAS No.:106064-00-0
Molecular Formula:C₂₃H₂₉NO₄
Molecular Weight:383.488
Hs Code.:

Synonyms:BRN 2166788;(Z)-3-(2-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-3-buten-2-one;3-Buten-2-one, 3-(2-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-, (Z)-;106064-00-0;LS-47284

Suppliers and Price of (Z)-3-(2-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-3-buten-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (Z)-3-(2-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-3-buten-2-one

Chemical Property:

Vapor Pressure:8.77E-14mmHg at 25°C
Boiling Point:569°C at 760 mmHg
Flash Point:297.9°C
Density:1.121g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:383.20965841
Heavy Atom Count:28
Complexity:505

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C(=CC1=CC=CC=C1)OC2=CC=CC=C2OCC(CNC(C)(C)C)O
Isomeric SMILES:CC(=O)/C(=C/C1=CC=CC=C1)/OC2=CC=CC=C2OCC(CNC(C)(C)C)O

Technology Process of (Z)-3-(2-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-3-buten-2-one

There total 5 articles about (Z)-3-(2-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)phenoxy)-3-buten-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 75-64-9
tert-butylamine

: 106063-61-0
(Z)-3-<2-(2,3-epoxypropoxy)phenoxy>-4-phenyl-3-buten-2-one

: 106064-00-0
(Z)-3-[2-(3-tert-Butylamino-2-hydroxy-propoxy)-phenoxy]-4-phenyl-but-3-en-2-one

Guidance literature:: In ethanol; for 36h; Heating;
DOI:10.1021/jm00388a005

Reference yield:

: 22965-96-4
(Z)-3-bromo-4-phenyl-3-buten-2-one

: 106064-00-0
(Z)-3-[2-(3-tert-Butylamino-2-hydroxy-propoxy)-phenoxy]-4-phenyl-but-3-en-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) K₂CO₃, 2.) 10percent aq. NaOH / 1.) acetone, reflux, 4 h. 2.) ethyl ether

2: 31 percent / NaOH / H₂O / 48 h / Ambient temperature

3: 42 percent / ethanol / 36 h / Heating

With sodium hydroxide; potassium carbonate; In ethanol; water;
DOI:10.1021/jm00388a005

Reference yield:

: 120-80-9,19481-10-8,37349-32-9
benzene-1,2-diol

: 106064-00-0
(Z)-3-[2-(3-tert-Butylamino-2-hydroxy-propoxy)-phenoxy]-4-phenyl-but-3-en-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) K₂CO₃, 2.) 10percent aq. NaOH / 1.) acetone, reflux, 4 h. 2.) ethyl ether

2: 31 percent / NaOH / H₂O / 48 h / Ambient temperature

3: 42 percent / ethanol / 36 h / Heating

With sodium hydroxide; potassium carbonate; In ethanol; water;
DOI:10.1021/jm00388a005