Bromofluoromethane

Base Information

• Chemical Name: Bromofluoromethane
• CAS No.: 373-52-4
• Molecular Formula: CH2BrF
• Molecular Weight: 112.929
• Hs Code.: 2903799090
• UNII: 22205E7CEM
• DSSTox Substance ID: DTXSID3074319
• Nikkaji Number: J110.453E
• Wikipedia: Bromofluoromethane
• Wikidata: Q765816
• Mol file: 373-52-4.mol

Synonyms:(18F)bromofluoromethane;bromofluoromethane

Chemical Property of Bromofluoromethane

Chemical Property:

• Appearance/Colour: Clear colourless to light yellow liquid
• Vapor Pressure: 4860mmHg at 25°C
• Refractive Index: 1.259
• Boiling Point: 19 °C at 760 mmHg
• Flash Point: None
• PSA: 0.00000
• Density: 1.773 g/cm³
• LogP: 1.30830
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 111.93239
• Heavy Atom Count: 3
• Complexity: 4.8

Purity/Quality:

99.0% ^*data from raw suppliers

BROMOFLUOROMETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(F)Br

Technology Process of Bromofluoromethane

There total 7 articles about Bromofluoromethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.1%

dibromofluoromethane (1868-53-7) → bromofluoromethane (373-52-4)

Guidance literature:

Reference yield:

silver(I) monofluoroacetate (13126-91-5) → bromofluoromethane (373-52-4)

Guidance literature:

With bromine; at 20 - 80 ℃; for 1h;

DOI:10.1016/S0022-2860(99)00251-3

Reference yield:

→ bromofluoromethane (373-52-4)

Guidance literature:

With bromine;

DOI:10.1039/jr9520004259

upstream raw materials:

dibromofluoromethane

halon-1211

methane

Bromotrifluoromethane

Downstream raw materials:

flixotide

17α-(cyclohexylmethylcarbonyl)oxy-6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-androsta-1,4-diene-17β-carbothioic acid S-fluoromethyl ester

2-chloro-4-fluoro-1-(fluoromethoxy)benzene

fluticasone furoate

Refernces

• 1、 Feller, Michael,Lux, Karin,Kornath, Andreas. "Crystal Structure and Spectroscopic Investigation of Bromofluoro- and Fluoroiodomethane". . p. 5357 - 5362. Retrieved 2016/01/25.
• 2、 Lijser, Huub J. P. de,Louw, Robert,Mulder, Peter. "Thermal Gas Phase Hydrodehalogenation of Bromochlorodifluoromethane". . p. 139 - 146. Retrieved 2007/10/02.