Propanamide, 3-[[2-hydroxy-3-[2-(4-morpholinyl)phenoxy]propyl](phenylmethyl)amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Base Information

Chemical Name:Propanamide, 3-[[2-hydroxy-3-[2-(4-morpholinyl)phenoxy]propyl](phenylmethyl)amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-
CAS No.:111794-51-5
Molecular Formula:C₃₄H₄₁N₅O₅
Molecular Weight:599.73
Hs Code.:
Mol file:111794-51-5.mol

Propanamide,
3-[[2-hydroxy-3-[2-(4-morpholinyl)phenoxy]propyl](phenylmethyl)amino]-
N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

Synonyms:

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Chemical Property of Propanamide, 3-[[2-hydroxy-3-[2-(4-morpholinyl)phenoxy]propyl](phenylmethyl)amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

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Technology Process of Propanamide, 3-[[2-hydroxy-3-[2-(4-morpholinyl)phenoxy]propyl](phenylmethyl)amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-

There total 3 articles about Propanamide, 3-[[2-hydroxy-3-[2-(4-morpholinyl)phenoxy]propyl](phenylmethyl)amino]- N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41536-44-1
2-(4-morpholinyl)-phenol

: 111794-51-5
3-{Benzyl-[2-hydroxy-3-(2-morpholin-4-yl-phenoxy)-propyl]-amino}-N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: base

2: propan-1-ol / Heating

With base; In propan-1-ol;
DOI:10.1021/jm00397a013

Reference yield:

: 111794-34-4
6-<4-(3-bromopropionamido)phenyl>-5-methyl-4,5-dihydro-3(2H)-pyridazinone

: 111794-51-5
3-{Benzyl-[2-hydroxy-3-(2-morpholin-4-yl-phenoxy)-propyl]-amino}-N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / propan-1-ol / 6 h / Heating

2: propan-1-ol / Heating

In propan-1-ol;
DOI:10.1021/jm00397a013

Reference yield:

: 36725-28-7
6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

: 111794-51-5
3-{Benzyl-[2-hydroxy-3-(2-morpholin-4-yl-phenoxy)-propyl]-amino}-N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenyl]-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / acetonitrile / 3 h / Heating

2: 81 percent / propan-1-ol / 6 h / Heating

3: propan-1-ol / Heating

In propan-1-ol; acetonitrile;
DOI:10.1021/jm00397a013