Technology Process of 1-(2,2-dimethylpropyl)-5-phenyl-1H-imidazole
There total 4 articles about 1-(2,2-dimethylpropyl)-5-phenyl-1H-imidazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
1,2-dichloro-benzene;
at 200 ℃;
for 1.5h;
regioselective reaction;
Microwave irradiation;
DOI:10.1039/c3cc48467j
- Guidance literature:
-
Multi-step reaction with 2 steps
1: phosphorus oxychloride, triethylamine / 1,2-dimethoxy-ethane / 1 h / 0 °C
2: methanol / Ambient temperature
With
triethylamine; trichlorophosphate;
In
methanol; 1,2-dimethoxyethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium tert-butoxide / 1,2-dimethoxy-ethane
2: phosphorus oxychloride, triethylamine / 1,2-dimethoxy-ethane / 1 h / 0 °C
3: methanol / Ambient temperature
With
potassium tert-butylate; triethylamine; trichlorophosphate;
In
methanol; 1,2-dimethoxyethane;
