2-Phenyl-2-(2-(2-phenyl-1,3-dithiolan-2-yl)ethyl)thiazolidine

Base Information

• Chemical Name: 2-Phenyl-2-(2-(2-phenyl-1,3-dithiolan-2-yl)ethyl)thiazolidine
• CAS No.: 156000-22-5
• Molecular Formula: C₂₀H₂₃NS₃
• Molecular Weight: 373.607
• DSSTox Substance ID: DTXSID30935351
• Nikkaji Number: J577.563I
• Mol file: 156000-22-5.mol

Synonyms:2-Phenyl-2-(2-(2-phenyl-1,3-dithiolan-2-yl)ethyl)thiazolidine;Thiazolidine, 2-phenyl-2-(2-(2-phenyl-1,3-dithiolan-2-yl)ethyl)-;156000-22-5;C20H23NS3;DTXSID30935351;2-phenyl-2-[2-(2-phenyl-1,3-dithiolan-2-yl)ethyl]-1,3-thiazolidine;C20-H23-N-S3;LS-151514;2-[2-(2-Phenyl-1,3-dithiolan-2-yl)ethyl]-2-phenylthiazolidine

Chemical Property of 2-Phenyl-2-(2-(2-phenyl-1,3-dithiolan-2-yl)ethyl)thiazolidine

Chemical Property:

• Vapor Pressure: 3.51E-12mmHg at 25°C
• Boiling Point: 550.8°C at 760 mmHg
• Flash Point: 286.9°C
• Density: 1.202g/cm³
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 373.09926326
• Heavy Atom Count: 24
• Complexity: 398

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CSC(N1)(CCC2(SCCS2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 2-Phenyl-2-(2-(2-phenyl-1,3-dithiolan-2-yl)ethyl)thiazolidine

There total 2 articles about 2-Phenyl-2-(2-(2-phenyl-1,3-dithiolan-2-yl)ethyl)thiazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenacylacetophenone (495-71-6) → 2-Phenyl-2-[2-(2-phenyl-[1,3]dithiolan-2-yl)-ethyl]-thiazolidine (156000-22-5)

Guidance literature:

Multi-step reaction with 2 steps

1: p-toluenesulfonic acid / toluene / 6 h / Heating

2: pyridine / 14 h / Heating

With pyridine; toluene-4-sulfonic acid; In toluene;

DOI:10.1016/0223-5234(94)90208-9

Reference yield:

2-mercaptoethylamine hydrochloride (156-57-0) + 1-Phenyl-3-(2-phenyl-[1,3]dithiolan-2-yl)-propan-1-one → 2-Phenyl-2-[2-(2-phenyl-[1,3]dithiolan-2-yl)-ethyl]-thiazolidine (156000-22-5)

Guidance literature:

With pyridine; for 14h; Yield given; Heating;

DOI:10.1016/0223-5234(94)90208-9

upstream raw materials:

2-mercaptoethylamine hydrochloride

phenacylacetophenone