(3R,4S)-3,4-diphenylcyclopentanone

Base Information

• Chemical Name: (3R,4S)-3,4-diphenylcyclopentanone
• CAS No.: 5452-60-8
• Molecular Formula: C17H16O
• Molecular Weight: 236.313
• Mol file: 5452-60-8.mol

Synonyms:

Chemical Property of (3R,4S)-3,4-diphenylcyclopentanone

Chemical Property:

• Vapor Pressure: 1.01E-05mmHg at 25°C
• Boiling Point: 371.7°C at 760 mmHg
• Flash Point: 161.3°C
• Density: 1.106g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3R,4S)-3,4-diphenylcyclopentanone

There total 24 articles about (3R,4S)-3,4-diphenylcyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,4-diphenylcyclopent-3-enone (7402-06-4) → meso 3,4-diphenyl-1-cyclopentanone (5452-60-8)

Guidance literature:

With palladium 10% on activated carbon; In ethyl acetate; for 4h;

DOI:10.1021/ja2092163

Reference yield: 50.0%

cis-1,1-dibromo-3,4-diphenylcyclopentane → meso 3,4-diphenyl-1-cyclopentanone (5452-60-8)

Guidance literature:

With acetic anhydride; triethylamine; In dichloromethane; water; at 20 ℃; for 1h;

DOI:10.1002/asia.201403277

Reference yield:

4-hydroxy-3,4-diphenylcyclopent-2-en-1-one (5587-78-0) → meso 3,4-diphenyl-1-cyclopentanone (5452-60-8)

Guidance literature:

With potassium hydroxide; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/0040-4020(69)80005-0

upstream raw materials:

meso-3,4-diphenyl-adipic acid dimethyl ester

ethyl cinnamate

4-hydroxy-3,4-diphenylcyclopent-2-en-1-one

phenyl cinnamate

Downstream raw materials:

(+/-)-cis-1.2-diphenyl-cyclopentanone-⁽⁴⁾-oxime

cis-1,2-diphenylcylopentane

(1R,2S)-4-(4-iodobenzyl)-1,2-diphenyl-1,2,3,4-tetrahydrocyclopenta[b]indole

2-((cis)-3,4-diphenylcyclopentylidene)-1-(4-iodobenzyl)-1-phenylhydrazine