4-HYDROXY-3,4-DIPHENYL-CYCLOPENT-2-ENONE

Base Information

• Chemical Name: 4-HYDROXY-3,4-DIPHENYL-CYCLOPENT-2-ENONE
• CAS No.: 5587-78-0
• Molecular Formula: C17H14O2
• Molecular Weight: 250.297
• Hs Code.: 2914400090
• Mol file: 5587-78-0.mol

Synonyms:4-Hydroxy-3,4-diphenyl-2-cyclopenten-1-on;3,4-diphenyl-4-hydroxycyclopent-2-en-1-one;4-hydroxy-3,4-diphenyl-2-cyclopenten-1-one;3,4-diphenyl-4-hydroxy-2-cyclopentene-1-one;4-hydroxy-3,4-diphenylcyclopent-2-enone;3,4-diphenyl-4-hydroxy-cyclopent-2-enone;

Chemical Property of 4-HYDROXY-3,4-DIPHENYL-CYCLOPENT-2-ENONE

Chemical Property:

• Vapor Pressure: 6.23E-06mmHg at 25°C
• Boiling Point: 363.8°Cat760mmHg
• Flash Point: 155.2°C
• PSA: 37.30000
• Density: 1.249g/cm³
• LogP: 2.93060

Purity/Quality:

3,4-DIPHENYL-4-HYDROXY-2-CYCLOPENTEN-1-ONE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXY-3,4-DIPHENYL-CYCLOPENT-2-ENONE

There total 20 articles about 4-HYDROXY-3,4-DIPHENYL-CYCLOPENT-2-ENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

benzil (134-81-6) + acetone (67-64-1) → 4-hydroxy-3,4-diphenylcyclopent-2-en-1-one (5587-78-0)

Guidance literature:

With potassium hydroxide; In ethanol; at 20 ℃; for 168000h;

DOI:10.1139/V06-054

Reference yield: 92.0%

1,5-diphenyl-6-oxabicyclo[3.1.0]hexan-3-one (24105-52-0) → (S)-4-hydroxy-3,4-diphenylcyclopent-2-enone (5587-78-0)

Guidance literature:

With N-[3,5-bis(trifluoromethyl)phenyl]-N'-[(9R)-6'-methoxycinchonan-9-yl]thiourea; In dichloromethane; at -20 ℃; for 18h; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/anie.200903253

Reference yield: 51.0%

4-(1H-benzotriazol-1-yl)-1,2-diphenyl-2,4-cyclopentadien-1-ol (221696-19-1) → 4-hydroxy-3,4-diphenylcyclopent-2-en-1-one (5587-78-0)

Guidance literature:

With toluene-4-sulfonic acid; In acetic acid; for 0.5h; Heating;

DOI:10.1002/(SICI)1521-3897(199902)341:2<152::AID-PRAC152>3.0.CO;2-Y

upstream raw materials:

benzil

acetone

1.2-Diphenyl-4-carboxy-cyclopentadien-(1.3)

cis-1,2-Diphenyl-2-penten-1,4-dion

Downstream raw materials:

7,8-diphenyl-bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylic acid-2,3;5,6-dianhydride

4,5-diphenylphthalic anhydride

1,2-diphenylcyclopent-1-ene

4-chloro-3,4-diphenylcyclopent-2-en-1-one