Methyl 3-oxo-3-[(2-phenylethyl)amino]propanoate

Base Information

Chemical Name:Methyl 3-oxo-3-[(2-phenylethyl)amino]propanoate
CAS No.:112178-20-8
Molecular Formula:C12H15NO3
Molecular Weight:221.256
Hs Code.:
DSSTox Substance ID:DTXSID40566872
Wikidata:Q82452636

Synonyms:112178-20-8;Methyl 3-oxo-3-[(2-phenylethyl)amino]propanoate;DTXSID40566872

Suppliers and Price of Methyl 3-oxo-3-[(2-phenylethyl)amino]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Methyl 3-oxo-3-[(2-phenylethyl)amino]propanoate

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:221.10519334
Heavy Atom Count:16
Complexity:234

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC(=O)NCCC1=CC=CC=C1

Technology Process of Methyl 3-oxo-3-[(2-phenylethyl)amino]propanoate

There total 2 articles about Methyl 3-oxo-3-[(2-phenylethyl)amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 5781-53-3
monomethyl oxalyl chloride

: 64-04-0
phenethylamine

: 112178-20-8
methoxycarbonylaceto-2-phenylethylamide

Guidance literature:: With potassium carbonate; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1139/v87-015

Reference yield: 73.0%

: 64-04-0
phenethylamine

: 108-59-8
malonic acid dimethyl ester

: 112178-20-8
methoxycarbonylaceto-2-phenylethylamide

Guidance literature:: at 40 ℃; neat (no solvent);
DOI:10.1002/adsc.200900686

Reference yield:

: 1963-36-6
4-methoxycinnamaldehyde

: 112178-20-8
methoxycarbonylaceto-2-phenylethylamide

: C₂₂H₂₅NO₅

Guidance literature:: With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; In dichloromethane; at 3 ℃; for 24h; enantioselective reaction;
DOI:10.1002/adsc.200900686