108-59-8Relevant articles and documents
Catalytic oxidative decarboxylation of malic acid into dimethyl malonate in methanol with dioxygen
Liu, Junxia,Du, Zhongtian,Yang, Yanliang,Lu, Tianliang,Lu, Fang,Xu, Jie
, p. 2151 - 2154 (2012)
If you've got it, use it: Malic acid is converted into dimethyl malonate by a direct, one-pot process. The process is cyanide- and halide-free. Phosphovanadomolybdates serve as bifunctional catalysts, effecting the oxidative decarboxylation and esterification in a consecutive manner. Oxidative C-C bond cleavage first forms hemiacetals. The results serve as example for the production of valuable chemicals by fully utilizing the oxygen atoms and basic structure inherent to biomass products.
Liquid Phase Carbonylation with Solid Catalyst. Carboxy Methylation of Dihalo Methane with Group VIII Metals Supported on Active Carbon
Yagita, Hiroshi,Kuwahara, Hiroyuki,Omata, Kohji,Fujimoto, Kaoru
, p. 335 - 338 (1990)
It was found that cobalt supported on active carbon showed an excellent catalytic activity for the carbonylation of dibromo methane in the liquid phase.For example, when the reaction was conducted under the conditions of 140 deg C, P (CO) = 31 atm, the yields of dimethyl malonate and bromomethyl acetate were 34.4percent and 22.2percent, respectively.Pd and Rh also showed catalytic activities.
On the most powerful chemical traps for bis(methoxycarbonyl)carbene (=2-methoxy-1-(methoxycarbonyl)-2-oxoethylidene)
Shevchenko, Vladimir V.,Zhegalova, Natalya G.,Borzenko, Andey O.,Nikolaev, Valerij A.
, p. 501 - 509 (2008)
The efficiency and validity of different chemical substrates for trapping bis(methoxycarbonyl)carbene (=2-methoxy-1-(methoxycarbonyl)-2-oxoethylidene; 1) is dependent on the conditions of carbene generation. On conventional photolysis of dimethyldiazomalonate (=2-diazopropanedioic acid dimethyl ester; 2) by long-wave UV light (through a Pyrex filter, λ > 290 nm), the most powerful trap for carbene 1 in the series of substrates Me2S, MeOH, cyclohexane, and pyridine is Me2S (with an efficiency ratio of ca. 6 :4 : 2 : 1, resp.). When short-wave decomposition of diazomalonate 2 is employed (through a quartz filter, λ > 210 nm), more reliable and useful chemical traps for bis(methoxycarbonyl)carbene (1) are pyridine and cyclohexane, whose adducts with 1 are rather stable under short-wave-irradiation conditions. Application of alcohols for the trapping of 1 proves to be preferential when simultaneous monitoring of carbene and oxoketene formation during photolysis is necessary.
Esterification by ZrO2 and Mo-ZrO2 eco-friendly solid acid catalysts
Manohar, Basude,Reddy, Vangala R.,Reddy, Benjaram M.
, p. 3183 - 3187 (1998)
Esterification of mono- and dicarboxylic acids catalysed by single (ZrO2) and mixed oxide (Mo-ZrO2) eco-friendly solid acid catalysts is described. The Mo-ZrO2 catalyst exhibits better catalytic performance than ZrO2.
6-O-MALONYL-β-METHYL-D-GLUCOPYRANOSIDE FROM ROOTS OF RUMEX OBTUSIFOLIUS
Kasai, Takanori,Okuda, Michiko,Sakamura, Sadao
, p. 1131 - 1132 (1981)
From the methanol-soluble acidic fraction of Rumex obtusifolius 6-O-malonyl-β-methyl-D-glucopyranoside and ascorbalamic acid were isolated and identified.The identity of the former compound was confirmed by synthesis.Key Word Index- Rumex obtusifolius; Polygonaceae; roots; 6-O-malonyl-β-methyl-D-glucopyranoside; organic acids.
Palladium phthalocyaninesulfonate functionalized mesoporous polymer: A highly efficient photocatalyst for degradation of 4-chlorophenol under visible light irradiation
Xing, Rong,Wu, Lin,Fei, Zhenghao,Wu, Peng
, p. 15 - 20 (2013)
A novel sulfonated palladium phthalocyanine (PdPcS) modified FDU-15 mesoporous polymer (FDU-PdPcS) has been prepared by rationally chemical modification process. The PdPcS molecules were highly dispersed inside the confined mesopores, and were further stabilized through a π-π interaction with mesopolymer, which may prevent the PdPcS molecules from agglomerating and deactivating in photodegradation reactions. The physicochemical properties of thus prepared FDU-PdPcS material were characterized by XRD, N2 adsorption-desorption, UV-vis and inductively coupled plasma techniques. FDU-PdPcS proved to be highly efficient heterogeneous photocatalyst for the degradation of 4-chlorophenol (4-CP) in the presence of H2O 2 under visible light irradiation. The photodegradation of 4-CP with an initial concentration 0.6 mM was completed within 5 h at pH 11 using a dose of 0.2 g/L of the 0.12 wt% FDU-PdPcS photocatalyst. The photodegradation intermediates were identified by GC-MS. A possible mechanism involved in the photodegradation of 4-CP has also been discussed.
Insight into the Claisen condensation of methyl acetate and dimethyl carbonate to dimethyl malonate
Zheng, Sainan,Xu, Shiwei,Zhou, Jinghong,Shen, Rongchun,Ji, Yang,Shen, Ming,Li, Wei
, p. 6689 - 6694 (2018)
A mechanistic study on the synthesis of dimethyl malonate (DMM) via condensation of methyl acetate (MA) and dimethyl carbonate (DMC), catalyzed by sodium methoxide, has been conducted using gas chromatography-mass spectrometry, liquid chromatography-electrospray ionization-mass spectrometry, X-ray diffraction, solid-state nuclear magnetic resonance spectroscopy and density functional theory calculations. The results indicated that the Claisen condensation of MA and DMC in the presence of methoxide yielded (CH3OCO)2CHNa (DMNa) instead of DMM since DMM is easily deprotonated by the methoxide catalyst. Further protonation after the condensation by adding a proton-donor reagent is essential to obtain DMM. Based on the experimental results, a detailed reaction mechanism for the condensation of MA and DMC into DMM in the presence of methoxide has been proposed and disclosed by computational calculations. Besides, it has been proven that the base strength of the catalyst has a critical effect on the condensation reaction and the DMM yield.
Modulation of cancer therapy using nano-organometallic compounds: Preparation, spectroscopic characterization and cytotoxic evaluation
El-Tabl, Abdou S.,Wahed, Moshira M. Abd-El,Mohamed, Eman A,Abu-Setta, Mohammed H. H.
, p. 3873 - 3887 (2021/07/17)
New series of Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) organometallic complexes with hydroxyl benzylidene malonohydrazide ligand have much potential as therapeutic and diagnostic agents. The ligand allows the thermodynamic and kinetic reactivity of the metal ion to be controlled and also provide a scaffold for functionalization. The establishment of structure activity relationships and elucidation of the specification of complexes under conditions relevant to drug testing and formulation are crucial for the further development of promising medicinal applications of organometallic complexes. Specific examples involving the design of metal complexes as anticancer agents are discussed. These complexes have been synthesized and characterized by (1H-NMR, mass, IR, UV-VIS and ESR) spectroscopy, as well as magnetic moments, conductance, elemental and thermal analyses. Molar conductance in DMF solution indicates that, the complexes are non-electrolytes. The ESR spectra of solid Cu(II) complexes (7) and (8) showed isotropic and anisotropic types indicating an octahedral geometry with covalent bond character. However, Co(II) complexes (3) and (4) showed anisotropic type where, g g >2.0023, indicating compressed tetragonal distortion around Co(II) ion. Cytotoxic evolution of the ligand and its complexes have been carried out. Complexes showed enhanced activity in comparison to the parent ligand or standard drug applied.
Method for preparing diacid diester compound under catalysis of deep eutectic solvent
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Paragraph 0035-0038, (2021/05/19)
The invention belongs to the technical field of organic synthesis, and discloses a method for preparing a diacid diester compound through catalysis of a deep eutectic solvent, wherein the deep eutectic solvent takes ammonium salt and ferric salt as hydrogen acceptors, takes p-toluenesulfonic acid as a hydrogen donor, takes diacid or anhydride of the diacid and an alcohol compound as raw materials, and adopts a one-pot method to prepare the diacid diester compound; and under the catalysis of the deep eutectic solvent, the esterification reaction is performed to generate the diester product. The selected deep eutectic solvent has characteristics of environmental protection, easy preparation, cheap components and easy recovery; the preparation method has characteristics of simple operation, simple separation, no water-carrying agent, repeated use of the deep eutectic solvent, and high diester yield.
Tailorable carbazolyl cyanobenzene-based photocatalysts for visible light-induced reduction of aryl halides
Ou, Wei,Zou, Ru,Han, Mengting,Yu, Lei,Su, Chenliang
supporting information, p. 1899 - 1902 (2019/12/27)
Herein, a series of carbazolyl cyanobenzene (CCB)-based organic photocatalysts with a broad range of photoredox capabilities were designed and synthesized, allowing precise control of the photocatalytic reactivity for the controllable reduction of aryl halides via a metal-free process. The screened-out CCB (5CzBN), a metal-free, low-cost, scalable and sustainable photocatalyst with both strong oxidative and reductive ability, exhibits superior performance for both dehalogenation and C[sbnd]C bond-forming arylation reactions.
