Chemical Property of Nitidine chloride
Chemical Property:
- Vapor Pressure:3.01E-15mmHg at 25°C
- Melting Point:281-282oC
- Refractive Index:1.696
- Boiling Point:619oC at 760 mmHg
- Flash Point:189.4oC
- PSA：40.80000
- Density:1.35g/cm3
- LogP:3.71660
- Storage Temp.:?20°C
- Solubility.:DMSO: soluble1mg/mL, clear (warmed)
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:2
- Exact Mass:383.0924357
- Heavy Atom Count:27
- Complexity:516
- Purity/Quality:
-
≥98% *data from raw suppliers
Nitidine Chloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC)OC.[Cl-]
-
Description
This quaternary alkaloid occurs primarily in Zanthoxylum nitidum (Lam.) DC
but has also been found in several species of Fagara. It is normally isolated as the
chloride which forms bright yellow needles when recrystallized from EtOH-HCl.
The crystals decompose on heating to 240°C yielding a product having m.p.
285-6°C. The iodide also forms yellow needles and undergoes a similar trans_x0002_formation at the same temperature to yield a product with the same melting point, possibly identical to that obtained from the chloride. The crystalline
acetate, m.p. 255-260°C and the pseudocyanide, m.p. 215-6°C and decomposing completely at 234°C in vacuo have also been prepared. A periodide, which
fonns chocolate-brown needles when crystallized from Me2CO, m.p. 300-1 °c
(dec.) is useful for characterizing the base.
