2-[2-(Benzyloxy)propan-2-yl]oxirane

Base Information

• Chemical Name: 2-[2-(Benzyloxy)propan-2-yl]oxirane
• CAS No.: 112482-34-5
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• DSSTox Substance ID: DTXSID50554063
• Mol file: 112482-34-5.mol

Synonyms:112482-34-5;2-[2-(Benzyloxy)propan-2-yl]oxirane;DTXSID50554063

Chemical Property of 2-[2-(Benzyloxy)propan-2-yl]oxirane

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 192.115029749
• Heavy Atom Count: 14
• Complexity: 183

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C1CO1)OCC2=CC=CC=C2

Technology Process of 2-[2-(Benzyloxy)propan-2-yl]oxirane

There total 1 articles about 2-[2-(Benzyloxy)propan-2-yl]oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-(benzyloxy)-3-methyl-1-butene (26902-24-9) → 2-(benzyloxy)-3,4-epoxy-2-methylbutane (112482-34-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; for 14h; Ambient temperature;

DOI:10.1021/jo00240a017

Reference yield: 30.0%

2-(benzyloxy)-3,4-epoxy-2-methylbutane (112482-34-5) + 2,3,4,6,2',3',6'-hepta-O-benzyl-α,α-D-trehalose (103128-34-3) → C73H80O13

Guidance literature:

With 15-crown-5; sodium hydride; In N,N-dimethyl-formamide; at 70 ℃; for 18h; Cooling with ice;

Reference yield:

2-(benzyloxy)-3,4-epoxy-2-methylbutane (112482-34-5) → 3-(benzyloxy)-1-fluoro-3-methylbutan-2-ol (112482-42-5) + 3-Benzyloxy-2-fluoro-3-methyl-butan-1-ol (112482-43-6)

Guidance literature:

With fluorhydrate de diisopropylamine; at 110 ℃; for 15h; Yield given. Yields of byproduct given;

DOI:10.1021/jo00240a017

upstream raw materials:

3-(benzyloxy)-3-methyl-1-butene

Downstream raw materials:

3-(benzyloxy)-1-fluoro-3-methylbutan-2-ol

3-Benzyloxy-2-fluoro-3-methyl-butan-1-ol