1-Azetidinesulfonic acid, 2-methyl-4-oxo-3-[2-oxo-2-[(phenylmethyl)amino]ethyl]-, monopotassium salt, cis-

Base Information

Chemical Name:1-Azetidinesulfonic acid, 2-methyl-4-oxo-3-[2-oxo-2-[(phenylmethyl)amino]ethyl]-, monopotassium salt, cis-
CAS No.:112634-22-7
Molecular Formula:C₁₃H₁₅N₂O₅S*K
Molecular Weight:350.437
Hs Code.:

Synonyms:

Suppliers and Price of 1-Azetidinesulfonic acid, 2-methyl-4-oxo-3-[2-oxo-2-[(phenylmethyl)amino]ethyl]-, monopotassium salt, cis-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-Azetidinesulfonic acid, 2-methyl-4-oxo-3-[2-oxo-2-[(phenylmethyl)amino]ethyl]-, monopotassium salt, cis-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Azetidinesulfonic acid, 2-methyl-4-oxo-3-[2-oxo-2-[(phenylmethyl)amino]ethyl]-, monopotassium salt, cis-

There total 9 articles about 1-Azetidinesulfonic acid, 2-methyl-4-oxo-3-[2-oxo-2-[(phenylmethyl)amino]ethyl]-, monopotassium salt, cis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [2-Hydroxymethyl-1-(4-methoxy-phenyl)-4-oxo-azetidin-3-yl]-thioacetic acid S-ethyl ester

: 112634-22-7
Potassium; 3-(benzylcarbamoyl-methyl)-2-methyl-4-oxo-azetidine-1-sulfonate

Guidance literature:: Multi-step reaction with 6 steps

1: triethylamine / CH₂Cl₂ / 1.) -78 deg C, 1 h, 2.) -78 deg C to room temp.

2: 89 percent / tetrapentylammonium iodide, KI / benzene / 20 h / Heating

3: 81 percent / tributyltin hydride / AIBN / benzene / 3 h / Heating

4: 84 percent / ceric ammonium nitrate / acetonitrile; H₂O / 0.5 h / -10 °C

5: 98 percent / 2 h / 70 °C

6: 1.) pyridine sulfur trioxide complex, 2.) Dowex 50X₈-200 ion exchange resin (potassium form) / 1.) pyridine, 80 deg C, 2 h

With ammonium cerium(IV) nitrate; Dowex 50X₈-200 ion exchange resin (potassium form); tri-n-butyl-tin hydride; sulfur trioxide pyridine complex; tetrapentylammonium iodide; triethylamine; potassium iodide; 2,2'-azobis(isobutyronitrile); In dichloromethane; water; acetonitrile; benzene;

Reference yield:

: [2-Formyl-1-(4-methoxy-phenyl)-4-oxo-azetidin-3-yl]-thioacetic acid S-ethyl ester

: 112634-22-7
Potassium; 3-(benzylcarbamoyl-methyl)-2-methyl-4-oxo-azetidine-1-sulfonate

Guidance literature:: Multi-step reaction with 7 steps

1: NaBH₄ / CH₂Cl₂ / 24 h

2: triethylamine / CH₂Cl₂ / 1.) -78 deg C, 1 h, 2.) -78 deg C to room temp.

3: 89 percent / tetrapentylammonium iodide, KI / benzene / 20 h / Heating

4: 81 percent / tributyltin hydride / AIBN / benzene / 3 h / Heating

5: 84 percent / ceric ammonium nitrate / acetonitrile; H₂O / 0.5 h / -10 °C

6: 98 percent / 2 h / 70 °C

7: 1.) pyridine sulfur trioxide complex, 2.) Dowex 50X₈-200 ion exchange resin (potassium form) / 1.) pyridine, 80 deg C, 2 h

With sodium tetrahydroborate; ammonium cerium(IV) nitrate; Dowex 50X₈-200 ion exchange resin (potassium form); tri-n-butyl-tin hydride; sulfur trioxide pyridine complex; tetrapentylammonium iodide; triethylamine; potassium iodide; 2,2'-azobis(isobutyronitrile); In dichloromethane; water; acetonitrile; benzene;

Reference yield:

: 112634-09-0
4-(iodomethylene)azetidinone

: 112634-22-7
Potassium; 3-(benzylcarbamoyl-methyl)-2-methyl-4-oxo-azetidine-1-sulfonate

Guidance literature:: Multi-step reaction with 4 steps

1: 81 percent / tributyltin hydride / AIBN / benzene / 3 h / Heating

2: 84 percent / ceric ammonium nitrate / acetonitrile; H₂O / 0.5 h / -10 °C

3: 98 percent / 2 h / 70 °C

4: 1.) pyridine sulfur trioxide complex, 2.) Dowex 50X₈-200 ion exchange resin (potassium form) / 1.) pyridine, 80 deg C, 2 h

With ammonium cerium(IV) nitrate; Dowex 50X₈-200 ion exchange resin (potassium form); tri-n-butyl-tin hydride; sulfur trioxide pyridine complex; 2,2'-azobis(isobutyronitrile); In water; acetonitrile; benzene;