Formamide, N-[2-[(trimethylsilyl)ethynyl]phenyl]-

Base Information

Chemical Name:Formamide, N-[2-[(trimethylsilyl)ethynyl]phenyl]-
CAS No.:112671-40-6
Molecular Formula:C12H15NOSi
Molecular Weight:217.343
Hs Code.:
DSSTox Substance ID:DTXSID90441069
Wikidata:Q82257636

Synonyms:112671-40-6;Formamide, N-[2-[(trimethylsilyl)ethynyl]phenyl]-;DTXSID90441069;N-(2-((Trimethylsilyl)ethynyl)phenyl)formamide

Suppliers and Price of Formamide, N-[2-[(trimethylsilyl)ethynyl]phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Formamide, N-[2-[(trimethylsilyl)ethynyl]phenyl]-

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:217.092290636
Heavy Atom Count:15
Complexity:281

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C#CC1=CC=CC=C1NC=O

Technology Process of Formamide, N-[2-[(trimethylsilyl)ethynyl]phenyl]-

There total 8 articles about Formamide, N-[2-[(trimethylsilyl)ethynyl]phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 10113-39-0
N-formyl-2-iodoaniline

: 1066-54-2
trimethylsilylacetylene

: 112671-40-6
2-(trimethylsilylethynyl)formanilide

Guidance literature:: With copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride;
DOI:10.1021/jo000831n

Reference yield: 45.0%

: 10113-38-9
N-(2-bromophenyl)formamide

: 1066-54-2
trimethylsilylacetylene

: 112671-40-6
2-(trimethylsilylethynyl)formanilide

Guidance literature:: With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; at 100 ℃; for 5h;

Reference yield:

: 615-43-0
2-iodophenylamine

: 112671-40-6
2-(trimethylsilylethynyl)formanilide

Guidance literature:: Multi-step reaction with 2 steps

1: diethylamine / tetrakis(triphenylphosphine)palladium⁽⁰⁾; copper(I) iodide / dimethylformamide / 6 h / 20 °C

2: tetrahydrofuran / 12 h / 0 °C

With diethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; N,N-dimethyl-formamide; 1: Sonogashira-Hagihara coupling;
DOI:10.1021/ol991133w