3-[(E)-3-(2-chlorophenyl)-2-methylprop-2-enoyl]-4,6-dimethyl-1H-pyridin-2-one

Base Information

Chemical Name:3-[(E)-3-(2-chlorophenyl)-2-methylprop-2-enoyl]-4,6-dimethyl-1H-pyridin-2-one
CAS No.:5376-17-0
Molecular Formula:C10H11 N3 O2 S
Molecular Weight:301.7674
Hs Code.:
DSSTox Substance ID:DTXSID80416822
Wikidata:Q82226399
Mol file:5376-17-0.mol

Synonyms:5376-17-0;3-[(E)-3-(2-chlorophenyl)-2-methylprop-2-enoyl]-4,6-dimethyl-1H-pyridin-2-one;ZINC04953382;DTXSID80416822;CCG-7683;BIM-0019571.P001;3-[3-(2-chlorophenyl)-2-methylacryloyl]-4,6-dimethyl-2(1H)-pyridinone

Suppliers and Price of 3-[(E)-3-(2-chlorophenyl)-2-methylprop-2-enoyl]-4,6-dimethyl-1H-pyridin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 3-[(E)-3-(2-chlorophenyl)-2-methylprop-2-enoyl]-4,6-dimethyl-1H-pyridin-2-one

Chemical Property:

Vapor Pressure:1.78E-10mmHg at 25°C
Boiling Point:508.9°Cat760mmHg
Flash Point:261.6°C
Density:1.217g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:301.0869564
Heavy Atom Count:21
Complexity:557

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=O)N1)C(=O)C(=CC2=CC=CC=C2Cl)C)C
Isomeric SMILES:CC1=CC(=C(C(=O)N1)C(=O)/C(=C/C2=CC=CC=C2Cl)/C)C

Technology Process of 3-[(E)-3-(2-chlorophenyl)-2-methylprop-2-enoyl]-4,6-dimethyl-1H-pyridin-2-one

There total 2 articles about 3-[(E)-3-(2-chlorophenyl)-2-methylprop-2-enoyl]-4,6-dimethyl-1H-pyridin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1225387-53-0
3⁽⁵⁾-aminopyrazole

: 98-59-9
p-toluenesulfonyl chloride

: 5376-17-0
2-tosyl-2H-pyrazol-3-ylamine

Guidance literature:: With sodium hydrogencarbonate; In acetonitrile; at 20 ℃; for 2h;
DOI:10.3390/ph9020019

Reference yield:

: 5376-17-0
2-tosyl-2H-pyrazol-3-ylamine

Guidance literature:: Neben 5-(p-Toluolsulfamino)pyrazol aus 3(5)-Aminopyrazol mit Tosylchlorid/Pyridin/90grad/1h Trennung in 2n NaOH;

Reference yield:

: 4-(4-chloro-6-methyl-pyrimidin-2-ylmethyl)-piperidine-1-carboxylic acid tert-butyl ester

: 5376-17-0
2-tosyl-2H-pyrazol-3-ylamine

: C₂₆H₃₄N₆O₄S

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; In water; toluene; at 140 ℃; for 2h; Microwave irradiation;
DOI:10.1111/cbdd.12733