6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE

Base Information

Chemical Name:6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE
CAS No.:112758-85-7
Molecular Formula:C8H12N2
Molecular Weight:136.19400
Hs Code.:
Mol file:112758-85-7.mol

Synonyms:6-METHYL-1H,2H,3H,4H-PYRROLO[1,2-A]PYRAZINE;6-Methyl-1,2,3,4-tetrahydro-pyrrolo[1,2-a]pyrazine;

Suppliers and Price of 6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE 95.00%
5MG
$ 498.97

AccelPharmtech
1,2,3,4-tetrahydro-6-methyl-Pyrrolo[1,2-a]pyrazine 97.00%
5G
$ 2750.00

Total 2 raw suppliers

Chemical Property of 6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE

Chemical Property:

Boiling Point:122-123 °C(Press: 8 Torr)
PKA:8.83±0.20(Predicted)
PSA：16.96000
Density:1.14±0.1 g/cm3(Predicted)
LogP:1.22850

Purity/Quality:

98%min ^*data from raw suppliers

6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE

There total 4 articles about 6-METHYL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 74583-40-7
6-Methyl-3-oxo-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazin

: 112758-85-7
6-methyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 70 ℃; for 1h;
DOI:10.1016/j.tetlet.2013.02.067

Reference yield:

: 85780-31-0
6-methyl-3,4-dihydropyrrolo<1,2-a>pyrazine

: 112758-85-7
6-methyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; Yield given; Heating;
DOI:10.1007/BF01145551

Reference yield:

: 14003-16-8
5-methylfurfurylamine

: 112758-85-7
6-methyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 1 h / -15 °C

2.1: hydrogenchloride; acetic acid / water / 12 h / 0 - 20 °C

2.2: 3 h / pH Ca_. 7 / Reflux

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 70 °C

With 4-methyl-morpholine; hydrogenchloride; lithium aluminium tetrahydride; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/j.tetlet.2013.02.067